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GMNN and HOXA10
Number of citations of the paper that reports this interaction (PMID
14973489
)
53
Data Source:
HPRD
(in vitro)
GMNN
HOXA10
Gene Name
geminin, DNA replication inhibitor
homeobox A10
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleus
Transcription Factor Complex
Cytoplasm
Molecular Function
Transcription Corepressor Activity
Protein Binding
Histone Deacetylase Binding
Repressing Transcription Factor Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Protein Binding
Histone Deacetylase Binding
Biological Process
Mitotic Cell Cycle
Protein Complex Assembly
Negative Regulation Of DNA Replication
Organ Morphogenesis
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Skeletal System Development
Transcription, DNA-templated
Multicellular Organismal Development
Spermatogenesis
Single Fertilization
Male Gonad Development
Anterior/posterior Pattern Specification
Proximal/distal Pattern Formation
Embryonic Limb Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Uterus Development
Pathways
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Removal of licensing factors from origins
CDT1 association with the CDC6:ORC:origin complex
Association of licensing factors with the pre-replicative complex
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Drugs
Diseases
GWAS
Dental caries (
23259602
)
Protein-Protein Interactions
26 interactors:
ARNT
AURKA
CASP3
CCDC146
CDKN1A
CDKN2A
CDT1
CSNK2A1
HDAC1
HOXA10
HOXA11
HOXA7
HOXB7
HOXC8
HOXC9
HOXD10
IMPDH1
KAT7
MCM6
NCF1
PHC1
REPIN1
SCMH1
SIX3
SMARCA4
ZNF439
12 interactors:
CREBBP
EMX1
EP300
FOXO1
GMNN
MEIS1
PBX1
POLR3D
PTPN6
SIRT2
SNAPC1
SPI1
Entrez ID
51053
3206
HPRD ID
06783
00845
Ensembl ID
ENSG00000112312
ENSG00000253293
Uniprot IDs
O75496
P31260
PDB IDs
1T6F
1UII
2LP0
2WVR
4BRY
Enriched GO Terms of Interacting Partners
?
Anterior/posterior Pattern Specification
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Pattern Specification Process
Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Embryonic Morphogenesis
Anatomical Structure Morphogenesis
Gene Expression
Embryonic Organ Development
Embryonic Organ Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Embryo Development
Proximal/distal Pattern Formation
Embryonic Skeletal System Morphogenesis
Regulation Of Cell Cycle
Multicellular Organismal Development
Negative Regulation Of Cell Cycle
Developmental Process
Skeletal System Morphogenesis
Organ Morphogenesis
Regulation Of Cell Cycle Process
Embryonic Limb Morphogenesis
Embryonic Skeletal System Development
Regulation Of Metabolic Process
Limb Morphogenesis
Skeletal System Development
Metabolic Process
Chromatin Modification
Limb Development
Organ Development
System Development
Anatomical Structure Development
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Transcription, DNA-templated
Immune System Process
Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Response To Oxygen Levels
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Nitrogen Compound Metabolic Process
Cell Development
Protein Acetylation
Negative Regulation Of Cell Differentiation
N-terminal Peptidyl-lysine Acetylation
Stem Cell Maintenance
Positive Regulation Of Transcription, DNA-templated
Innate Immune Response
Organ Development
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Gene Expression
Regulation Of Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Anatomical Structure Morphogenesis
Gene Expression
Multicellular Organismal Development
Stem Cell Development
Regulation Of Gene Expression
Peptidyl-lysine Modification
Cellular Macromolecule Biosynthetic Process
Anatomical Structure Development
Negative Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Positive Regulation Of Type I Interferon Production
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Stem Cell Differentiation
N-terminal Protein Amino Acid Acetylation
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Immune Response
Developmental Process
Regulation Of Type I Interferon Production
Negative Regulation Of Gene Expression
System Development
Defense Response
Tagcloud
?
contrary
coordination
definitive
drives
e2
elevate
epigenetic
eralpha
ere
ere1
ere2
eres
extensively
h3k4
haematopoiesis
homeobox
knockdown
leukaemia
lineage
methylase
mll
mll1
much
oestrogen
recruiting
start
suppresses
transcriptionally
way
Tagcloud (Difference)
?
contrary
coordination
definitive
drives
e2
elevate
epigenetic
eralpha
ere
ere1
ere2
eres
extensively
h3k4
haematopoiesis
homeobox
knockdown
leukaemia
lineage
methylase
mll
mll1
much
oestrogen
recruiting
start
suppresses
transcriptionally
way
Tagcloud (Intersection)
?