Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SHANK1 and LPHN1
Number of citations of the paper that reports this interaction (PMID
10964907
)
14
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
SHANK1
LPHN1
Gene Name
SH3 and multiple ankyrin repeat domains 1
latrophilin 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Cytoplasm
Plasma Membrane
Ionotropic Glutamate Receptor Complex
Membrane
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Neuron Projection
Dendritic Spine
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Plasma Membrane
Integral Component Of Membrane
Cell Junction
Axon
Growth Cone
Presynaptic Membrane
Neuron Projection
Synapse
Molecular Function
Protein Binding
Protein C-terminus Binding
SH3 Domain Binding
GKAP/Homer Scaffold Activity
Somatostatin Receptor Binding
Protein Complex Binding
Ionotropic Glutamate Receptor Binding
Identical Protein Binding
Ankyrin Repeat Binding
Scaffold Protein Binding
G-protein Coupled Receptor Activity
Protein Binding
Latrotoxin Receptor Activity
Carbohydrate Binding
Cell Adhesion Molecule Binding
Biological Process
Protein Complex Assembly
Cytoskeletal Anchoring At Plasma Membrane
Long-term Memory
Associative Learning
Adult Behavior
Negative Regulation Of Actin Filament Bundle Assembly
Social Behavior
Protein Localization To Synapse
Olfactory Behavior
Habituation
Neuromuscular Process Controlling Balance
Determination Of Affect
Righting Reflex
Synapse Maturation
Dendritic Spine Morphogenesis
Positive Regulation Of Dendritic Spine Development
Vocalization Behavior
Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
G-protein Coupled Receptor Signaling Pathway
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Synapse Maturation
Pathways
Drugs
Diseases
GWAS
Mortality among heart failure patients (
20400778
)
Protein-Protein Interactions
17 interactors:
ABCA1
ARHGEF7
BAI2
BAIAP2
DLG4
DLGAP1
DNM2
HOMER1
LPHN1
LPHN2
RPS6KA2
RPS6KA3
SHARPIN
SPTAN1
SSTR2
STAT1
TANC1
9 interactors:
ANKS1A
APC
CACNA1A
DLG3
DLG4
PSMA3
ROS1
SHANK1
SHANK2
Entrez ID
50944
22859
HPRD ID
05413
14305
Ensembl ID
ENSG00000161681
Uniprot IDs
H9KV90
Q9Y566
O94910
PDB IDs
Enriched GO Terms of Interacting Partners
?
Synaptic Transmission
Neuron Projection Morphogenesis
Cell Projection Organization
Signaling
Nervous System Development
Cell Communication
Neuron Projection Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cell Surface Receptor Signaling Pathway
Axonogenesis
Response To External Stimulus
Anatomical Structure Development
Cell-cell Signaling
Axon Development
Regulation Of Cellular Component Organization
System Development
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Development
Cell Differentiation
Signal Transduction
Cell Morphogenesis
Developmental Process
Axon Guidance
Neuron Differentiation
Cell Morphogenesis Involved In Differentiation
Response To Stimulus
Multicellular Organismal Development
Cell Development
Apoptotic Process
Cellular Response To Stimulus
Programmed Cell Death
Chemotaxis
Generation Of Neurons
Cell Death
Death
Protein Localization To Synapse
Neurogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Dendritic Spine Organization
G-protein Coupled Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Response To Organic Substance
Cellular Response To Organic Substance
Regulation Of Cell Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Response To Bacterium
Neurotrophin TRK Receptor Signaling Pathway
Response To Nutrient
Neurotrophin Signaling Pathway
Vocalization Behavior
Protein Localization To Synapse
Synapse Organization
Neuron Development
Social Behavior
Cell Development
Receptor Clustering
Neuron Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Morphogenesis
Nervous System Development
Neuromuscular Process Controlling Balance
Synapse Assembly
Cell Morphogenesis Involved In Differentiation
Receptor Localization To Synapse
Dendrite Morphogenesis
Neuron Projection Development
Generation Of Neurons
Cell Projection Morphogenesis
Dendritic Spine Morphogenesis
Cell Part Morphogenesis
Neurogenesis
Membrane Depolarization
Neuromuscular Process
Single-organism Behavior
Learning
Dendritic Spine Development
Dendrite Development
Regulation Of Signaling
Cell Morphogenesis
Dendritic Spine Organization
Anatomical Structure Development
Adult Behavior
Reflex
Cell Projection Organization
Cell Differentiation
Exploration Behavior
Synaptic Transmission
Behavior
Establishment Or Maintenance Of Apical/basal Cell Polarity
Regulation Of Ion Transport
Developmental Process
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Signaling
Cell Communication
Positive Regulation Of Membrane Potential
Learning Or Memory
Regulation Of Membrane Potential
System Development
Cognition
Tagcloud
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Difference)
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
gtf2f1
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Intersection)
?