SHANK1 and BAI2

Number of citations of the paper that reports this interaction (PMID 10964907)
14

Data Source:
HPRD (two hybrid)

		SHANK1	BAI2
Gene Name		SH3 and multiple ankyrin repeat domains 1	brain-specific angiogenesis inhibitor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Plasma Membrane Ionotropic Glutamate Receptor Complex Membrane N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Neuron Projection Dendritic Spine Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Somatostatin Receptor Binding Protein Complex Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Ankyrin Repeat Binding Scaffold Protein Binding	G-protein Coupled Receptor Activity
	Biological Process	Protein Complex Assembly Cytoskeletal Anchoring At Plasma Membrane Long-term Memory Associative Learning Adult Behavior Negative Regulation Of Actin Filament Bundle Assembly Social Behavior Protein Localization To Synapse Olfactory Behavior Habituation Neuromuscular Process Controlling Balance Determination Of Affect Righting Reflex Synapse Maturation Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential	G-protein Coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ABCA1 ARHGEF7 BAI2 BAIAP2 DLG4 DLGAP1 DNM2 HOMER1 LPHN1 LPHN2 RPS6KA2 RPS6KA3 SHARPIN SPTAN1 SSTR2 STAT1 TANC1	8 interactors: ARHGAP1 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13
Entrez ID		50944	576
HPRD ID		05413	04063
Ensembl ID		ENSG00000161681	ENSG00000121753
Uniprot IDs		H9KV90 Q9Y566	O60241
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Neuron Projection Morphogenesis Cell Projection Organization Signaling Nervous System Development Cell Communication Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cell Surface Receptor Signaling Pathway Axonogenesis Response To External Stimulus Anatomical Structure Development Cell-cell Signaling Axon Development Regulation Of Cellular Component Organization System Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Cell Differentiation Signal Transduction Cell Morphogenesis Developmental Process Axon Guidance Neuron Differentiation Cell Morphogenesis Involved In Differentiation Response To Stimulus Multicellular Organismal Development Cell Development Apoptotic Process Cellular Response To Stimulus Programmed Cell Death Chemotaxis Generation Of Neurons Cell Death Death Protein Localization To Synapse Neurogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Dendritic Spine Organization G-protein Coupled Receptor Signaling Pathway Anatomical Structure Morphogenesis Response To Organic Substance Cellular Response To Organic Substance Regulation Of Cell Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Bacterium Neurotrophin TRK Receptor Signaling Pathway Response To Nutrient Neurotrophin Signaling Pathway	Vocalization Behavior Synapse Organization Social Behavior Regulation Of Vasoconstriction By Circulating Norepinephrine Determination Of Affect Memory Learning Sensory Processing Habituation Adult Behavior Nonassociative Learning Negative Regulation Of Peptidyl-cysteine S-nitrosylation Righting Reflex Synapse Maturation Olfactory Behavior Learning Or Memory Regulation Of Membrane Potential Cognition Cytoskeletal Anchoring At Plasma Membrane Dendritic Spine Morphogenesis Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chemosensory Behavior Long Term Synaptic Depression Dendritic Spine Development Protein Localization To Synapse Regulation Of Actin Filament-based Process Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Ventricular Cardiac Muscle Cell Action Potential Regulation Of Ion Transmembrane Transport Dendritic Spine Organization Reflex Regulation Of Membrane Repolarization Regulation Of Signaling Single-organism Behavior Positive Regulation Of Dendritic Spine Development Exploration Behavior Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetic epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetic epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Intersection) ?