SHANK1 and BAIAP2

Number of citations of the paper that reports this interaction (PMID 12504591)
14

Data Source:
BioGRID (two hybrid, far western blotting, affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		SHANK1	BAIAP2
Gene Name		SH3 and multiple ankyrin repeat domains 1	BAI1-associated protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Plasma Membrane Ionotropic Glutamate Receptor Complex Membrane N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Neuron Projection Dendritic Spine Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Filopodium Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein C-terminus Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Somatostatin Receptor Binding Protein Complex Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Ankyrin Repeat Binding Scaffold Protein Binding	Protein Binding Protein C-terminus Binding Cytoskeletal Adaptor Activity Identical Protein Binding Proline-rich Region Binding
	Biological Process	Protein Complex Assembly Cytoskeletal Anchoring At Plasma Membrane Long-term Memory Associative Learning Adult Behavior Negative Regulation Of Actin Filament Bundle Assembly Social Behavior Protein Localization To Synapse Olfactory Behavior Habituation Neuromuscular Process Controlling Balance Determination Of Affect Righting Reflex Synapse Maturation Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Dendrite Development Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Synaptic Plasticity Actin Filament Bundle Assembly Actin Crosslink Formation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ABCA1 ARHGEF7 BAI2 BAIAP2 DLG4 DLGAP1 DNM2 HOMER1 LPHN1 LPHN2 RPS6KA2 RPS6KA3 SHARPIN SPTAN1 SSTR2 STAT1 TANC1	32 interactors: APP ATN1 BAI1 C14orf1 C19orf25 CDC42 DIAPH1 ENAH EPS8 ESPN KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3B4 SHANK1 SHANK2 SRPK2 TP53BP2 WASF1 WASF2 WASL YWHAG
Entrez ID		50944	10458
HPRD ID		05413	05686
Ensembl ID		ENSG00000161681	ENSG00000175866
Uniprot IDs		H9KV90 Q9Y566	B4DWA1 I3L4C2 Q9UQB8
PDB IDs			1WDZ 1Y2O 2YKT 3RNJ
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Neuron Projection Morphogenesis Cell Projection Organization Signaling Nervous System Development Cell Communication Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cell Surface Receptor Signaling Pathway Axonogenesis Response To External Stimulus Anatomical Structure Development Cell-cell Signaling Axon Development Regulation Of Cellular Component Organization System Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Cell Differentiation Signal Transduction Cell Morphogenesis Developmental Process Axon Guidance Neuron Differentiation Cell Morphogenesis Involved In Differentiation Response To Stimulus Multicellular Organismal Development Cell Development Apoptotic Process Cellular Response To Stimulus Programmed Cell Death Chemotaxis Generation Of Neurons Cell Death Death Protein Localization To Synapse Neurogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Dendritic Spine Organization G-protein Coupled Receptor Signaling Pathway Anatomical Structure Morphogenesis Response To Organic Substance Cellular Response To Organic Substance Regulation Of Cell Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Bacterium Neurotrophin TRK Receptor Signaling Pathway Response To Nutrient Neurotrophin Signaling Pathway	Regulation Of Cytoskeleton Organization Nervous System Development Regulation Of Organelle Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cell Projection Organization System Development Multicellular Organismal Development Maintenance Of Cell Polarity Generation Of Neurons Actin Cytoskeleton Organization Developmental Process Neuron Projection Development Actin Filament Organization Actin Filament-based Process Neurogenesis Cytoskeleton Organization Cell Projection Organization Regulation Of Cell Projection Assembly Regulation Of Actin Cytoskeleton Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuron Development Protein Localization To Basolateral Plasma Membrane Locomotion Regulation Of Actin Filament-based Process Maintenance Of Epithelial Cell Apical/basal Polarity Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cellular Protein Localization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Projection Organization Maintenance Of Apical/basal Cell Polarity Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Localization Actin Polymerization Or Depolymerization Neuron Differentiation Regulation Of Cell Morphogenesis Establishment Or Maintenance Of Cell Polarity Cell Differentiation Cell Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Signaling Cellular Component Assembly Cell Communication Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Development Cell Morphogenesis
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?