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SHANK1
Gene Name
SH3 and multiple ankyrin repeat domains 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Cytoplasm
Plasma Membrane
Ionotropic Glutamate Receptor Complex
Membrane
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Neuron Projection
Dendritic Spine
Postsynaptic Membrane
Excitatory Synapse
Neuronal Postsynaptic Density
Molecular Function
Protein Binding
Protein C-terminus Binding
SH3 Domain Binding
GKAP/Homer Scaffold Activity
Somatostatin Receptor Binding
Protein Complex Binding
Ionotropic Glutamate Receptor Binding
Identical Protein Binding
Ankyrin Repeat Binding
Scaffold Protein Binding
Biological Process
Protein Complex Assembly
Cytoskeletal Anchoring At Plasma Membrane
Long-term Memory
Associative Learning
Adult Behavior
Negative Regulation Of Actin Filament Bundle Assembly
Social Behavior
Protein Localization To Synapse
Olfactory Behavior
Habituation
Neuromuscular Process Controlling Balance
Determination Of Affect
Righting Reflex
Synapse Maturation
Dendritic Spine Morphogenesis
Positive Regulation Of Dendritic Spine Development
Vocalization Behavior
Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
17 interactors:
ABCA1
ARHGEF7
BAI2
BAIAP2
DLG4
DLGAP1
DNM2
HOMER1
LPHN1
LPHN2
RPS6KA2
RPS6KA3
SHARPIN
SPTAN1
SSTR2
STAT1
TANC1
Entrez ID
50944
HPRD ID
05413
Ensembl ID
ENSG00000161681
Uniprot IDs
H9KV90
Q9Y566
PDB IDs
Enriched GO Terms of Interacting Partners
?
Synaptic Transmission
Neuron Projection Morphogenesis
Cell Projection Organization
Signaling
Nervous System Development
Cell Communication
Neuron Projection Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Cell Surface Receptor Signaling Pathway
Axonogenesis
Response To External Stimulus
Anatomical Structure Development
Cell-cell Signaling
Axon Development
Regulation Of Cellular Component Organization
System Development
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Development
Cell Differentiation
Signal Transduction
Cell Morphogenesis
Developmental Process
Axon Guidance
Neuron Differentiation
Cell Morphogenesis Involved In Differentiation
Response To Stimulus
Multicellular Organismal Development
Cell Development
Apoptotic Process
Cellular Response To Stimulus
Programmed Cell Death
Chemotaxis
Generation Of Neurons
Cell Death
Death
Protein Localization To Synapse
Neurogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Dendritic Spine Organization
G-protein Coupled Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Response To Organic Substance
Cellular Response To Organic Substance
Regulation Of Cell Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Response To Bacterium
Neurotrophin TRK Receptor Signaling Pathway
Response To Nutrient
Neurotrophin Signaling Pathway
Tagcloud
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deltan
eef1a1
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interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
sumo1
sypl1
tkt
topbp1
znf668