Description |
notch receptor 4 |
presenilin 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- A body shape index ( 34021172)
- Age-related macular degeneration ( 22694956)
- Aspartate aminotransferase levels ( 29403010)
- Asthma ( 21804548 31619474)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Bipolar disorder ( 31043756)
- Blood protein levels in cardiovascular risk ( 28369058)
- Chronic hepatitis B infection ( 25802187)
- Circulating myeloperoxidase levels (serum) ( 23620142)
- Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
- Colorectal cancer ( 30529582)
- Crohn's disease ( 23266558)
- Epstein-Barr virus immune response (EBNA-1) ( 23326239)
- Femur bone mineral density x serum urate levels interaction ( 34046847)
- Food antigen IgG levels ( 24962563)
- Hematocrit ( 32888494)
- Hemoglobin ( 32888494)
- High light scatter reticulocyte count ( 32888494)
- Hip circumference adjusted for BMI ( 34021172)
- HIV-1 control ( 20041166)
- Inflammatory bowel disease ( 28067908)
- Iron status biomarkers (iron levels) ( 28334935)
- Joint mobility (Beighton score) ( 27182965)
- Longevity ( 30294719)
- Lung cancer ( 31577861 28604730)
- Lung cancer in ever smokers ( 28604730)
- Lupus nephritis in systemic lupus erythematosus ( 24925725)
- Migraine ( 27322543)
- Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
- Obesity-related traits ( 23251661)
- Objective response to lithium treatment in bipolar disorder ( 26503763)
- Prostate cancer ( 23535732)
- Reticulocyte count ( 32888494)
- Reticulocyte fraction of red cells ( 27863252)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
- Schizophrenia ( 23894747 19571808 30285260)
- Soluble receptor for advanced glycation end-product levels ( 26083729)
- Squamous cell lung carcinoma ( 28604730)
- Systemic lupus erythematosus ( 32771030 21408207)
- Systemic sclerosis ( 21779181)
- Takayasu arteritis ( 25604533)
- Type 1 diabetes (age at diagnosis) ( 33179336)
- Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
- Ulcerative colitis ( 28067908 24837172)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for body mass index ( 28448500)
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Interacting Genes |
13 interacting genes:
DLL4
EGFL7
ELOC
FBXW7
MAML1
MAML2
MAML3
PSEN1
PSEN2
RBPJ
SMAD2
SMAD3
SMAD4
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92 interacting genes:
ACTN1
AP1M2
APBA1
APH1A
APH1B
APOE
APP
BACE1
BCL2
BCL2L1
CASP1
CASP3
CASP4
CASP6
CASP7
CASP8
CDH1
CDK5
CFL1
CIB1
CTNNA1
CTNNB1
CTNND1
CTNND2
CYP2C18
CYP2C8
DLL1
DOCK3
ECSIT
EFHD1
EFNB2
ENSA
EPB41L3
ERN1
ETFA
FBXL12
FBXW7
FGF13
FLNA
FLNB
GAPDH
GCDH
GDI1
GFAP
GSK3B
HERPUD1
HMGB1
ICAM5
ITSN2
JUP
KANK2
KCNIP3
KCNIP4
MAPK9
MAPT
METTL2B
MTCH1
NCSTN
NOS3
NOTCH1
NOTCH2
NOTCH3
NOTCH4
OXCT1
PDCD4
PIK3R1
PKP4
PRAM1
PRDX2
PRKACA
PRKCZ
PSENEN
PSMA5
PSMB1
RAB11A
RAB3A
RAD23A
RHEB
RMDN3
RNF32
RYR2
SCAF11
SCN1A
SLC10A6
ST13
STAMBPL1
TCF7L2
TDP2
TUBA1B
UBQLN1
UMPS
YME1L1
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Entrez ID |
4855 |
5663 |
HPRD ID |
01290 |
00087 |
Ensembl ID |
ENSG00000204301
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ENSG00000080815
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Uniprot IDs |
A0A1U9X983
Q99466
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A0A024R6A3
A0A0S2Z4D2
P49768
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PDB IDs |
7OR3
7OR5
7OR7
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2KR6
4UIS
5A63
5FN2
5FN3
5FN4
5FN5
6IDF
6IYC
6LQG
6LR4
7C9I
7D8X
7Y5T
8IM7
8K8E
8KCO
8KCP
8KCS
8KCT
8KCU
8OQY
8OQZ
8X52
8X53
8X54
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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