NOTCH4 and FBXW7

  • Number of citations of the paper that reports this interaction (PMID 11585921)
  • 71
  • Data Source:
  • HPRD (in vivo)

NOTCH4

FBXW7

Gene Name notch 4 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 13 interactors: DLL4 EGFL7 FBXW7 MAML1 MAML2 MAML3 PSEN1 PSEN2 RBPJ SMAD2 SMAD3 SMAD4 TCEB1 33 interactors: ARL6IP1 CCNE1 CCNE2 CDC34 CREB3L1 CREB3L2 CUL1 EBNA1BP2 FAM101A GLMN GNB2L1 HEY1 HIPK2 JUN KIAA1875 KLF5 LINGO1 MCL1 MED13 MED13L MMS22L MYB MYC NOTCH1 NOTCH4 PARK2 PPARGC1A PSEN1 SHPRH SKP1 STOML1 SUMF2 UBE2D1
Entrez ID 4855 55294
HPRD ID 01290 05888
Ensembl ID ENSG00000204301 ENSG00000109670
Uniprot IDs Q99466 B7Z2C8 G0Z2K0 Q969H0 S4R3U4
PDB IDs 2OVP 2OVQ 2OVR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
antileukemic  antiproliferative  apigenin  baicalein  cdc2  cdk4  cdk6  chrysin  division  dysregulated  dysregulation  flavonoids  galangin  genistein  hl  illustrated  jurkat  k562  luteolin  naringenin  nb4  potencies  ppa  proteomic  scutellarin  suppresses  u937  ubiquitously  xiap 
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Difference) ?
antileukemic  antiproliferative  apigenin  baicalein  cdc2  cdk4  cdk6  chrysin  division  dysregulated  dysregulation  flavonoids  galangin  genistein  hl  illustrated  jurkat  k562  luteolin  naringenin  nb4  potencies  ppa  proteomic  scutellarin  suppresses  u937  ubiquitously  xiap 
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Intersection) ?