| Name |
notch receptor 4 |
delta like canonical Notch ligand 4 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| GWAS |
- A body shape index ( 34021172
)
- Age-related macular degeneration ( 22694956
)
- Aspartate aminotransferase levels ( 29403010
)
- Asthma ( 21804548
31619474
)
- Autism spectrum disorder or schizophrenia ( 28540026
)
- Bipolar disorder ( 31043756
)
- Blood protein levels in cardiovascular risk ( 28369058
)
- Chronic hepatitis B infection ( 25802187
)
- Circulating myeloperoxidase levels (serum) ( 23620142
)
- Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947
)
- Colorectal cancer ( 30529582
)
- Crohn's disease ( 23266558
)
- Epstein-Barr virus immune response (EBNA-1) ( 23326239
)
- Femur bone mineral density x serum urate levels interaction ( 34046847
)
- Food antigen IgG levels ( 24962563
)
- Hematocrit ( 32888494
)
- Hemoglobin ( 32888494
)
- High light scatter reticulocyte count ( 32888494
)
- Hip circumference adjusted for BMI ( 34021172
)
- HIV-1 control ( 20041166
)
- Inflammatory bowel disease ( 28067908
)
- Iron status biomarkers (iron levels) ( 28334935
)
- Joint mobility (Beighton score) ( 27182965
)
- Longevity ( 30294719
)
- Lung cancer ( 31577861
28604730
)
- Lung cancer in ever smokers ( 28604730
)
- Lupus nephritis in systemic lupus erythematosus ( 24925725
)
- Migraine ( 27322543
)
- Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430
)
- Obesity-related traits ( 23251661
)
- Objective response to lithium treatment in bipolar disorder ( 26503763
)
- Prostate cancer ( 23535732
)
- Reticulocyte count ( 32888494
)
- Reticulocyte fraction of red cells ( 27863252
)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848
)
- Schizophrenia ( 23894747
19571808
30285260
)
- Soluble receptor for advanced glycation end-product levels ( 26083729
)
- Squamous cell lung carcinoma ( 28604730
)
- Systemic lupus erythematosus ( 32771030
21408207
)
- Systemic sclerosis ( 21779181
)
- Takayasu arteritis ( 25604533
)
- Type 1 diabetes (age at diagnosis) ( 33179336
)
- Type 1 diabetes and autoimmune thyroid diseases ( 25936594
)
- Ulcerative colitis ( 28067908
24837172
)
- Waist circumference adjusted for body mass index ( 34021172
)
- Waist-hip index ( 34021172
)
- Waist-to-hip ratio adjusted for BMI ( 34021172
)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500
)
- Waist-to-hip ratio adjusted for body mass index ( 28448500
)
|
|
| Novel Interactors |
9 novel interactors:
MSH5
NEU1
NFKBIL1
NFYA
PBX2
PSMB8
SLC27A4
TDP2
WWP2
|
1 novel interactors:
PAK6
|
| Interacting Genes |
13 interacting genes:
DLL4
EGFL7
ELOC
FBXW7
MAML1
MAML2
MAML3
PSEN1
PSEN2
RBPJ
SMAD2
SMAD3
SMAD4
|
2 interacting genes:
NOTCH1
NOTCH4
|
| Entrez ID |
4855 |
54567 |
| HPRD ID |
01290
|
05540
|
| Ensembl ID |
ENSG00000204301
|
ENSG00000128917
|
| Uniprot IDs |
A0A1U9X983
Q99466
|
Q9NR61
|
| PDB IDs |
7OR3
7OR5
7OR7
|
5MVX
|
| GO Terms Enriched among Interactors |
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|