NEDD8 and CUL1

  • Number of citations of the paper that reports this interaction (PMID 10713156)
  • 100
  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vivo, in vitro)

NEDD8

CUL1

Gene Name neural precursor cell expressed, developmentally down-regulated 8 cullin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 34 interactors: AHR ANK1 ARIH1 ARIH2 CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B CUL5 DCUN1D1 DNMT3B NAE1 NPLOC4 NUB1 PARP1 PSMD4 PTK2 RPL11 SENP8 SMURF1 TP53 UBA2 UBA3 UBE2F UBE2K UBE2M UBXN7 UCHL1 UCHL3 UFD1L 55 interactors: ARIH1 BTRC CAND1 CDC34 CDCA3 CDK9 CDKN1B CENPE CHEK1 CHUK CKS1B COMMD1 COPS2 COPS5 COPS6 COPS7A COPS8 DCUN1D4 E2F1 FBXO18 FBXO25 FBXW11 FBXW2 FBXW4 FBXW7 GLMN GPS1 HIPK2 NEDD8 NFKBIA NFKBIB NFKBIE NLK NR1D2 PARK2 PPP1CA PRPF40A PSMB4 PSMD4 PTTG1 RAC2 RANBP2 RBX1 RICTOR RNF7 SENP8 SKP1 SKP2 SMAD3 THRA TRIM21 UBE2E3 UBE2F UBE2M ZC3HC1
Entrez ID 4738 8454
HPRD ID 04412 04389
Ensembl ID ENSG00000129559 ENSG00000055130
Uniprot IDs Q15843 B3KTW0 Q13616
PDB IDs 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 1LDJ 1LDK 1U6G 3RTR 3TDU 3TDZ 4F52
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  mitotic  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
Tagcloud (Difference) ?
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  mitotic  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
Tagcloud (Intersection) ?