NEDD8 and SMURF1

  • Number of citations of the paper that reports this interaction (PMID 24821572)
  • 3
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)

NEDD8

SMURF1

Gene Name neural precursor cell expressed, developmentally down-regulated 8 SMAD specific E3 ubiquitin protein ligase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 34 interactors: AHR ANK1 ARIH1 ARIH2 CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B CUL5 DCUN1D1 DNMT3B NAE1 NPLOC4 NUB1 PARP1 PSMD4 PTK2 RPL11 SENP8 SMURF1 TP53 UBA2 UBA3 UBE2F UBE2K UBE2M UBXN7 UCHL1 UCHL3 UFD1L 98 interactors: ANAPC5 AP2B1 APBB2 APP ARHGAP15 ARHGAP31 ARHGEF9 ARL14 ARL4D ASH2L AVEN AXIN1 CCM2 CDC40 CDK14 CDKL1 CSNK2A2 CUL5 CXXC1 DNAJC7 DUSP13 DVL2 ECSIT ELP3 ESR1 ETV6 FBXL15 FBXO30 FCHO1 GNG11 GRIPAP1 HDGFRP3 ING2 INPP5B IRAK2 JUNB LATS1 LHX9 LIMS1 LONRF3 MAP3K2 MAP3K3 NAA16 NDFIP2 NEDD8 OXSR1 PAK1 PAK1IP1 PDLIM7 PLEKHO1 POLR2A PSME3 PWP1 RASD2 RHOA RHPN2 RIPK2 RIT1 RNF11 RNF141 RPS27A RRP9 RTKN RUNX3 SASH3 SENP8 SF3A1 SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SPG20 SQSTM1 SRSF4 SRSF5 STK35 STRAP STUB1 TLN1 TNK2 TNNT1 TRAF4 TTC17 UBA52 UBB UBC UBE2D3 UBE2L3 UBTF UBXN1 USP45 USP9X WDR61 WEE1 WFS1 XPO1
Entrez ID 4738 57154
HPRD ID 04412 06902
Ensembl ID ENSG00000129559 ENSG00000198742
Uniprot IDs Q15843 Q9HCE7
PDB IDs 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 2LAZ 2LB0 2LB1 2LTX 3PYC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
5p  acvr2a  alters  applying  bmp  bmp1a  cleaves  cluster  copyright  dies1  furin  impairs  interferes  mapk3  micrornas  mineralization  mir  osteoblast  osteoblasts  protected  reprogramming  reserved  rights  ski  smad  smad5  systematically  tgfbr3  zfp423 
Tagcloud (Difference) ?
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
5p  acvr2a  alters  applying  bmp  bmp1a  cleaves  cluster  copyright  dies1  furin  impairs  interferes  mapk3  micrornas  mineralization  mir  osteoblast  osteoblasts  protected  reprogramming  reserved  rights  ski  smad  smad5  systematically  tgfbr3  zfp423 
Tagcloud (Intersection) ?