SMAD7 and SMAD6

  • Number of citations of the paper that reports this interaction (PMID 9256479)
  • 43
  • Data Source:
  • HPRD (two hybrid, in vitro, in vivo)

SMAD7

SMAD6

Gene Name SMAD family member 7 SMAD family member 6
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions 54 interactors: ACVR1B AKT1 ASH1L AXIN1 BMPR1B CTNNB1 CXXC5 DVL1 EP300 ERBB2IP HAT1 HEYL KDM2A MAP2K3 MAP2K6 MAP3K7 MAPK14 MBD1 MKL2 MYOD1 NEDD4L PARD3 PARD3B PIAS1 PIAS4 RNF111 SASH3 SIRT1 SMAD2 SMAD4 SMAD6 SMURF1 SMURF2 SOX13 SOX5 SOX7 STAMBP STAMBPL1 STRAP TAB1 TGFB1I1 TGFBR1 TGFBR2 TTF1 TTF2 UBE2L3 UCHL5 WWP2 XRCC6 YAP1 ZBTB11 ZBTB44 ZEB1 ZNF107 16 interactors: BMPR1B HOXC8 MAP3K7 MAPK6 RNF111 RPS6KA5 RUNX2 SMAD1 SMAD7 SMURF1 SMURF2 STAMBP STRAP TAB1 TGFBR1 TOB1
Entrez ID 4092 4091
HPRD ID 04241 04240
Ensembl ID ENSG00000101665 ENSG00000137834
Uniprot IDs B3KYA8 O15105 O43541
PDB IDs 2DJY 2KXQ 2LTV 2LTW 2LTX 2LTY 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adp  beta1  blocks  decapentaplegic  deoxynucleotidyl  deoxyuridine  fibroblasts  fibrogenic  fibrotic  homolog  hydroxyproline  immunocytochemistry  mothers  myofibroblasts  nick  pd  peyronie  pretreated  quashed  ribose  smad2  smad3  terminate  tgf  transdifferentiation  transferase  transforming  triphosphate 
5fu  annotation  anticancer  array  chemoresistance  concluded  consequently  deacetylases  deacetylation  downregulate  fluorouracil  fu  hdac4  hdac4mediated  hdac4oe  hdacs  mb  mcf7  mda  morphogenetic  overexpressing  remodeling  restored  smad4  stably  summary  tgfbeta2  transforming  verify 
Tagcloud (Difference) ?
adp  beta1  blocks  decapentaplegic  deoxynucleotidyl  deoxyuridine  fibroblasts  fibrogenic  fibrotic  homolog  hydroxyproline  immunocytochemistry  mothers  myofibroblasts  nick  pd  peyronie  pretreated  quashed  ribose  smad2  smad3  terminate  tgf  transdifferentiation  transferase  triphosphate 
5fu  annotation  anticancer  array  chemoresistance  concluded  consequently  deacetylases  deacetylation  downregulate  fluorouracil  fu  hdac4  hdac4mediated  hdac4oe  hdacs  mb  mcf7  mda  morphogenetic  overexpressing  remodeling  restored  smad4  stably  summary  tgfbeta2  verify 
Tagcloud (Intersection) ?
transforming