LRP6 and LRRK2

  • Number of citations of the paper that reports this interaction (PMID 22899650)
  • 10
  • Data Source:
  • BioGRID (imaging technique, affinity chromatography technology, two hybrid)

LRP6

LRRK2

Gene Name low density lipoprotein receptor-related protein 6 leucine-rich repeat kinase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 15 interactors: ANTXR1 ANTXR2 APOB ATP13A2 AXIN1 DKK1 DKK2 FZD5 FZD8 GSK3B LRRK2 MESDC1 SERPINF1 WNT1 WNT3A 33 interactors: ACTB AKT1 ARFGAP1 ARHGEF7 BAG5 DVL1 DVL2 DVL3 EIF4EBP1 HSPD1 L3MBTL3 LRP6 MAP1B MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPT MBP PRKCZ PTPN23 RALYL RIPK2 SH3GL1 SH3GL2 SH3GL3 STK24 STK25 STK3 STRBP TAOK3 TRAF2 TUBA1A
Entrez ID 4040 120892
HPRD ID 04617 10613
Ensembl ID ENSG00000070018 ENSG00000188906
Uniprot IDs F5H7J9 O75581 Q17RV3 Q5S007
PDB IDs 3S2K 3S8V 3S8Z 3S94 3SOB 3SOQ 3SOV 4A0P 4DG6 2ZEJ 3D6T
Enriched GO Terms of Interacting Partners?
Tagcloud ?
3a  5a  7b  8b  9a  avian  axin2  branch  branching  canonical  characterizes  chick  crosstalk  dkk1  explants  fgf  fh535  gastrulation  governed  lrp5  morphogenesis  pk115  player  preserved  recapitulates  sfrp1  shh  vertebrate  wnt 
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
Tagcloud (Difference) ?
3a  5a  7b  8b  9a  avian  axin2  branch  branching  canonical  characterizes  chick  crosstalk  dkk1  explants  fgf  fh535  gastrulation  governed  lrp5  morphogenesis  pk115  player  preserved  recapitulates  sfrp1  shh  vertebrate  wnt 
autosomal  decline  difficulty  dj1  england  g2019s  gait  gu  hoehn  idiopathic  leucine  motor  movement  parkinson  pd  pigd  pink1  postural  prkn  rating  schwab  snca  society  staging  udrs  undefined  unified  updrs  yahr 
Tagcloud (Intersection) ?