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LAMB3 and COL7A1
Number of citations of the paper that reports this interaction (PubMedID
9989793
)
0
Data Source:
HPRD
(in vitro, in vivo)
LAMB3
COL7A1
Description
laminin subunit beta 3
collagen type VII alpha 1 chain
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Basement Membrane
Laminin-5 Complex
Extracellular Matrix
Extracellular Region
Collagen Trimer
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
COPII-coated ER To Golgi Transport Vesicle
Extracellular Matrix
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Molecular Function
Structural Molecule Activity
Extracellular Matrix Structural Constituent
Protein Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Peptidase Inhibitor Activity
Biological Process
Cell Adhesion
Epidermis Development
Cell Differentiation
Endodermal Cell Differentiation
Brown Fat Cell Differentiation
Cell Adhesion
Epidermis Development
Endodermal Cell Differentiation
Pathways
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Anchoring fibril formation
Laminin interactions
Laminin interactions
Non-integrin membrane-ECM interactions
Type I hemidesmosome assembly
MET activates PTK2 signaling
Attachment of bacteria to epithelial cells
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Developmental Lineage of Pancreatic Ductal Cells
Collagen degradation
Collagen degradation
Fibronectin matrix formation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
COPII-mediated vesicle transport
Integrin cell surface interactions
Anchoring fibril formation
Laminin interactions
Laminin interactions
Cargo concentration in the ER
Collagen chain trimerization
Drugs
Diseases
Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
Epidermolysis bullosa, dysprophic, including: ; Epidermolysis bullosa dystrophica, AD; Epidermolysis bullosa dystrophica, AR; Epidermolysis bullosa pruriginosa; Epidermolysis bullosa, pretibial
Transient bullous dermolysis of the newborn
GWAS
Fentanyl consumption in laparoscopic-assisted colectomy (first 24 hours) (
26566055
)
Age at first sexual intercourse (
27089180
)
Apolipoprotein A1 levels (
32203549
)
Bone fracture in osteoporosis (
28580392
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
6 interacting genes:
BMP1
COL7A1
LAMA3
LAMC2
MDFI
THBS1
15 interacting genes:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MIA3
MMP2
SHKBP1
THBS1
ZC3H7A
Entrez ID
3914
1294
HPRD ID
01032
00358
Ensembl ID
ENSG00000196878
ENSG00000114270
Uniprot IDs
A0A0S2Z3R6
Q13751
Q02388
Q59F16
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix
Basement Membrane
Extracellular Matrix Structural Constituent
Epidermis Development
Endodermal Cell Differentiation
Cell Adhesion
Extracellular Region
Collagen Type VII Trimer
Developmental Process
Extracellular Space
Laminin-2 Complex
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Collagen V Binding
Laminin-5 Complex
Laminin-3 Complex
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Tissue Development
Heparin Binding
Negative Regulation Of Dendritic Cell Antigen Processing And Presentation
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Hemidesmosome Assembly
Negative Regulation Of Endothelial Cell Chemotaxis
Positive Regulation Of Transforming Growth Factor Beta1 Production
Engulfment Of Apoptotic Cell
Negative Regulation Of CGMP-mediated Signaling
Negative Regulation Of Plasminogen Activation
Fibrinogen Binding
Hemidesmosome
Negative Regulation Of Fatty Acid Transport
Regulation Of Long-chain Fatty Acid Import Into Cell
Fibrinogen Complex
Regulation Of Cell Migration
Nitric Oxide-cGMP-mediated Signaling
Negative Regulation Of Antigen Processing And Presentation
Blood Coagulation, Fibrin Clot Formation
Chronic Inflammatory Response
Regulation Of Nitric Oxide Mediated Signal Transduction
Cell Differentiation
Endoplasmic Reticulum Lumen
Regulation Of Cell Motility
Regulation Of Locomotion
Negative Regulation Of Fibrinolysis
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Regulation Of CGMP-mediated Signaling
Proteoglycan Binding
Protein Maturation
Dorsal/ventral Axis Specification
Trophoblast Giant Cell Differentiation
Pattern Specification Process
Extracellular Matrix Structural Constituent
Extracellular Matrix
Basement Membrane
Extracellular Region
Regulation Of Cell Migration
Regulation Of Cell Motility
Regulation Of Locomotion
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Extracellular Space
Extracellular Structure Organization
Extracellular Matrix Organization
Laminin-5 Complex
Regulation Of Cell Adhesion
Endodermal Cell Differentiation
Endoplasmic Reticulum Lumen
Tube Morphogenesis
Morphogenesis Of An Epithelium
Intramembranous Ossification
Retinal Blood Vessel Morphogenesis
Bone Trabecula Formation
Fibrinogen Complex
Tissue Morphogenesis
Blood Coagulation, Fibrin Clot Formation
Retina Vasculature Morphogenesis In Camera-type Eye
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Platelet-derived Growth Factor Binding
Branching Involved In Salivary Gland Morphogenesis
Cellular Response To Amino Acid Stimulus
Proteoglycan Binding
Collagen-activated Signaling Pathway
Cell Adhesion
Negative Regulation Of NLRP3 Inflammasome Complex Assembly
Blood Vessel Morphogenesis
Protease Binding
Response To Hyperoxia
Animal Organ Development
Skeletal System Morphogenesis
Angiogenesis
Protein Activation Cascade
Negative Regulation Of Cell Adhesion
Response To Amino Acid
Anatomical Structure Morphogenesis
Ossification
Branching Morphogenesis Of An Epithelial Tube
Receptor Ligand Activity
Developmental Process
Ameboidal-type Cell Migration
Integrin Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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