LAMB3 and COL7A1

Number of citations of the paper that reports this interaction (PMID 9989793)
13

Data Source:
HPRD (in vitro, in vivo)

		LAMB3	COL7A1
Gene Name		laminin, beta 3	collagen, type VII, alpha 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Laminin-5 Complex	Extracellular Region Collagen Type VII Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Structural Molecule Activity Protein Binding Protein Complex Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Epidermis Development Extracellular Matrix Disassembly Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly Endodermal Cell Differentiation Brown Fat Cell Differentiation	Cell Adhesion Epidermis Development Negative Regulation Of Endopeptidase Activity Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation
Pathways		Cell junction organization Type I hemidesmosome assembly Collagen formation Laminin interactions Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Collagen formation Laminin interactions Collagen degradation Anchoring fibril formation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BMP1 COL7A1 LAMA3 LAMC2 THBS1	14 interactors: BMP1 COL1A1 COL4A1 FBXL2 FN1 HSPA8 LAMA1 LAMA5 LAMB3 LAMC2 MMP2 SHKBP1 THBS1 ZC3H7A
Entrez ID		3914	1294
HPRD ID		01032	00358
Ensembl ID		ENSG00000196878	ENSG00000114270
Uniprot IDs		Q13751	Q02388 Q59F16
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Tissue Development Hemidesmosome Assembly Epidermis Development Endodermal Cell Differentiation Cell Adhesion Cell-substrate Junction Assembly Endoderm Formation Endoderm Development Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Formation Of Primary Germ Layer Anatomical Structure Development Anatomical Structure Morphogenesis Engulfment Of Apoptotic Cell Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Gastrulation Cartilage Development Developmental Process Cell Junction Assembly Negative Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Nitric Oxide Mediated Signal Transduction Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Anatomical Structure Formation Involved In Morphogenesis Epithelium Development Negative Regulation Of Antigen Processing And Presentation Connective Tissue Development Regulation Of CGMP-mediated Signaling Negative Regulation Of Endopeptidase Activity Skeletal System Morphogenesis Negative Regulation Of Peptidase Activity Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of Plasminogen Activation Positive Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Fibrinolysis Negative Regulation Of Proteolysis Positive Regulation Of Fibroblast Migration Protein O-linked Fucosylation Positive Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Protein Processing Positive Regulation Of Macrophage Activation Regulation Of Endopeptidase Activity Cellular Response To Nitric Oxide Negative Regulation Of Hydrolase Activity Chronic Inflammatory Response Phagocytosis, Engulfment Regulation Of Fibrinolysis Regulation Of Protein Processing	Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Tissue Development Blood Vessel Development Vasculature Development Cell-substrate Junction Assembly Anatomical Structure Morphogenesis Blood Vessel Morphogenesis Locomotion Cardiovascular System Development Movement Of Cell Or Subcellular Component Anatomical Structure Formation Involved In Morphogenesis Angiogenesis Endodermal Cell Differentiation Cell Morphogenesis Involved In Differentiation Anatomical Structure Development Retinal Blood Vessel Morphogenesis Cell Junction Assembly Endoderm Formation Cellular Response To Amino Acid Stimulus Developmental Process Collagen Catabolic Process Organ Morphogenesis Intramembranous Ossification Collagen Metabolic Process Cell Morphogenesis Cell Differentiation Multicellular Organismal Macromolecule Metabolic Process Skeletal System Morphogenesis Bone Trabecula Formation Endoderm Development Multicellular Organismal Metabolic Process Multicellular Organismal Development Cell Adhesion Retina Vasculature Morphogenesis In Camera-type Eye Hemidesmosome Assembly Response To Amino Acid Bone Trabecula Morphogenesis Axon Guidance Formation Of Primary Germ Layer System Development Cell Projection Morphogenesis Cell Part Morphogenesis Retina Vasculature Development In Camera-type Eye Morphogenesis Of A Polarized Epithelium Cellular Response To Acid Chemical Branching Involved In Salivary Gland Morphogenesis Gastrulation Platelet Activation
Tagcloud ?		besides built c13orf18 ccl3 cish clustering comprising cytoreductive discriminators et fosb gadd45b granulocytes hrh4 id2 jak jak2v617f klf5 maff mutational pim1 signature socs2 socs3 stat supervised tagap thrombocythemia trib1
Tagcloud (Difference) ?		besides built c13orf18 ccl3 cish clustering comprising cytoreductive discriminators et fosb gadd45b granulocytes hrh4 id2 jak jak2v617f klf5 maff mutational pim1 signature socs2 socs3 stat supervised tagap thrombocythemia trib1
Tagcloud (Intersection) ?