KRT17 and CCDC85B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		KRT17	CCDC85B
Gene Name		keratin 17, type I	coiled-coil domain containing 85B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intermediate Filament Extracellular Vesicular Exosome Cell Periphery	Nucleus Cytoplasm Centrosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding MHC Class II Receptor Activity MHC Class II Protein Binding	Protein Binding
	Biological Process	Signal Transduction Epidermis Development Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APC CCDC85B EGFR KDM1A KRT6A KRT7 KRT72 KRT8 TRIM69 ZDHHC17	133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821
Entrez ID		3872	11007
HPRD ID		01019	16101
Ensembl ID		ENSG00000128422	ENSG00000175602
Uniprot IDs		Q04695 Q14666	Q15834
PDB IDs
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Chromosome Organization Hair Follicle Development Hair Cycle Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Astrocyte Activation Hair Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Gland Development Embryonic Placenta Development In Utero Embryonic Development Cell Differentiation Negative Regulation Of Protein Catabolic Process Regulation Of Response To DNA Damage Stimulus Activation Of Phospholipase A2 Activity Negative Regulation Of Odontogenesis Positive Regulation Of Phospholipase A2 Activity Muscle Cell Development Regulation Of Cell Proliferation Regulation Of Myeloid Cell Differentiation Response To Cobalamin Response To UV-A Placenta Development Response To Hydroxyisoflavone Metaphase/anaphase Transition Of Mitotic Cell Cycle Histone H3-K9 Demethylation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Histone H3-K4 Methylation Response To Hydrostatic Pressure Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Histone H3-K4 Demethylation Regulation Of Chromosome Organization	Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death
Tagcloud ?		aggressiveness axis basal blbc comprised concurrent cytokeratin cytokeratins cytoskeleton erk1 gaba gabrp hcc1187 hcc70 inherent krt14 krt5 krt6b maintains migratory poorer postulate protrusions silenced stably subtype therapeutics tn tumorigenic
Tagcloud (Difference) ?		aggressiveness axis basal blbc comprised concurrent cytokeratin cytokeratins cytoskeleton erk1 gaba gabrp hcc1187 hcc70 inherent krt14 krt5 krt6b maintains migratory poorer postulate protrusions silenced stably subtype therapeutics tn tumorigenic
Tagcloud (Intersection) ?