KRT17 and TRIM69

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT17	TRIM69
Gene Name		keratin 17, type I	tripartite motif containing 69
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intermediate Filament Extracellular Vesicular Exosome Cell Periphery	Nucleus Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding MHC Class II Receptor Activity MHC Class II Protein Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Signal Transduction Epidermis Development Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development	Apoptotic Process Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APC CCDC85B EGFR KDM1A KRT6A KRT7 KRT72 KRT8 TRIM69 ZDHHC17	22 interactors: APP ASNS ATP5G1 DVL1 FAM110A FKBP1B HAUS1 IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 ZNF483
Entrez ID		3872	140691
HPRD ID		01019	11518
Ensembl ID		ENSG00000128422	ENSG00000185880
Uniprot IDs		Q04695 Q14666	Q86WT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Chromosome Organization Hair Follicle Development Hair Cycle Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Astrocyte Activation Hair Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Gland Development Embryonic Placenta Development In Utero Embryonic Development Cell Differentiation Negative Regulation Of Protein Catabolic Process Regulation Of Response To DNA Damage Stimulus Activation Of Phospholipase A2 Activity Negative Regulation Of Odontogenesis Positive Regulation Of Phospholipase A2 Activity Muscle Cell Development Regulation Of Cell Proliferation Regulation Of Myeloid Cell Differentiation Response To Cobalamin Response To UV-A Placenta Development Response To Hydroxyisoflavone Metaphase/anaphase Transition Of Mitotic Cell Cycle Histone H3-K9 Demethylation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Histone H3-K4 Methylation Response To Hydrostatic Pressure Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Histone H3-K4 Demethylation Regulation Of Chromosome Organization	MRNA 3'-splice Site Recognition Collateral Sprouting Maintenance Of Protein Location In Nucleus Anatomical Structure Development System Development Negative Regulation Of Catalytic Activity Protein Localization To Nucleus Regulation Of Cell Development Developmental Process Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Cell Development Morphogenesis Of An Epithelium MRNA Splice Site Selection Multicellular Organismal Development Organ Development Positive Regulation Of Neuron Projection Development Regulation Of Neuron Differentiation Neuromuscular Junction Development Cellular Nitrogen Compound Metabolic Process Epithelium Development Negative Regulation Of Translation In Response To Oxidative Stress L-asparagine Biosynthetic Process Regulation Of Hormone Levels Anatomical Structure Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of Translation Spliceosomal Complex Assembly Positive Regulation Of Cell Projection Organization Tissue Morphogenesis Positive Regulation Of Cell Cycle Regulation Of Proteolysis Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Cell Differentiation Calcium Ion Homeostasis Regulation Of Neurogenesis Positive Regulation Of Protein Metabolic Process Gene Expression Cellular Component Assembly Regulation Of Calcium Ion Transport Into Cytosol Synaptic Growth At Neuromuscular Junction Positive Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Neuron Differentiation Nitrogen Compound Metabolic Process Response To Light Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aggressiveness axis basal blbc comprised concurrent cytokeratin cytokeratins cytoskeleton erk1 gaba gabrp hcc1187 hcc70 inherent krt14 krt5 krt6b maintains migratory poorer postulate protrusions silenced stably subtype therapeutics tn tumorigenic
Tagcloud (Difference) ?		aggressiveness axis basal blbc comprised concurrent cytokeratin cytokeratins cytoskeleton erk1 gaba gabrp hcc1187 hcc70 inherent krt14 krt5 krt6b maintains migratory poorer postulate protrusions silenced stably subtype therapeutics tn tumorigenic
Tagcloud (Intersection) ?