TAF3 and TAF10

Number of citations of the paper that reports this interaction (PubMedID 11438666)
57

Data Source:
HPRD (two hybrid, in vivo)

		TAF3	TAF10
Description		TATA-box binding protein associated factor 3	TATA-box binding protein associated factor 10
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GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Transcription Factor TFIID Complex Nuclear Membrane	SAGA Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm Transcription Preinitiation Complex
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding Protein Heterodimerization Activity Histone H3K4me3 Reader Activity Transcription Regulator Inhibitor Activity	DNA Binding Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Enzyme Binding Nuclear Estrogen Receptor Binding Identical Protein Binding RNA Polymerase Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of Signal Transduction By P53 Class Mediator	G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development Somitogenesis Liver Development Embryonic Placenta Development Regulation Of DNA Repair Chromatin Remodeling DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Apoptotic Process Gene Expression Regulation Of Gene Expression Multicellular Organism Growth SAGA Complex Assembly MRNA Transcription By RNA Polymerase II Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Lateral Mesodermal Cell Differentiation RNA Polymerase II Preinitiation Complex Assembly Limb Development Positive Regulation Of Transcription Initiation By RNA Polymerase II Protein-containing Complex Assembly Hepatocyte Differentiation Allantois Development
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Asthma ( 31959851) Cadmium levels ( 26025379) Red blood cell count ( 32888494)	Malaria ( 31844061)
Interacting Genes		6 interacting genes: H3-4 H3C1 HMGB1 KPNA2 KPNB1 TAF10	23 interacting genes: ATXN7 ESR1 FANCA FTL H3-4 POLR2A PSMC5 SETD7 TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIP12 UBE2I
Entrez ID		83860	6881
HPRD ID		19377	15972
Ensembl ID		ENSG00000165632	ENSG00000166337
Uniprot IDs		A0A8I5KR98 Q5VWG9	Q12962
PDB IDs		5C13 5WXG 5WXH 5XMY 6MZD 6MZL 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	2F69 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 4J7F 4J7I 4J83 4J8O 4WV4 5EG2 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGI 7EGJ 7ENA 7ENC 7KTR 7KTS 8GXQ 8GXS 8H7G 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		NLS-dependent Protein Nuclear Import Complex Positive Regulation Of Viral Life Cycle NLS-bearing Protein Import Into Nucleus Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity Protein-DNA Complex Assembly Chromatin Remodeling Chromatin Organization Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Positive Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Viral Process SAGA Complex Assembly Transferase Activity, Transferring One-carbon Groups Thymidylate Synthase Activity Regulation Of Transcription Initiation By RNA Polymerase II Adenylate Cyclase Regulator Activity Regulation Of DNA Metabolic Process Regulation Of Mismatch Repair Regulation Of DNA-templated Transcription Initiation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Regulation Of Viral Life Cycle Ficolin-1-rich Granule Lumen Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Negative Regulation Of Apoptotic Cell Clearance Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Regulation Of Viral Process Mitotic Chromosome Movement Towards Spindle Pole Import Into Nucleus Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus RNA Import Into Nucleus Viral Penetration Into Host Nucleus Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Lateral Mesodermal Cell Differentiation Allantois Development DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process DTTP Biosynthetic Process Nucleosome Nucleosome Assembly Nucleosome Organization Spermatogonial Cell Division	RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription By RNA Polymerase II Transcription Factor TFIID Complex MRNA Transcription RNA Polymerase II General Transcription Initiation Factor Activity Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Protein-DNA Complex Assembly Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation Transcription By RNA Polymerase II Transcription Factor TFTC Complex DNA-templated Transcription MRNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process Protein-containing Complex Assembly Nucleoplasm Protein Heterodimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein-containing Complex Organization TBP-class Protein Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of DNA Repair RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Cellular Component Assembly Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Metabolic Process MLL1 Complex Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Nucleus Macromolecule Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress SAGA Complex Regulation Of Gene Expression
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