AP3S2 and AP3S1

Number of citations of the paper that reports this interaction (PubMedID 9118953)
45

Data Source:
HPRD (in vivo, two hybrid)

		AP3S2	AP3S1
Description		adaptor related protein complex 3 subunit sigma 2	adaptor related protein complex 3 subunit sigma 1
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Golgi Apparatus Synaptic Vesicle Membrane Membrane Coat AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm	Early Endosome Golgi Apparatus Membrane Membrane Coat AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Presynapse Axon Cytoplasm
	Molecular Function		Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Melanosome Assembly	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Melanosome Assembly
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Type 2 diabetes ( 21874001 23945395 24509480 28869590 29358691 30054458 30297969 30718926 32499647) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		7 interacting genes: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4 SCARB2	7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3
Entrez ID		10239	1176
HPRD ID		03880	03298
Ensembl ID		ENSG00000157823	ENSG00000177879
Uniprot IDs		P59780	F5H459 Q92572
PDB IDs			9C58 9C59 9C5B 9C5C
Enriched GO Terms of Interacting Partners?		Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Intracellular Protein Transport AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Melanosome Assembly Platelet Dense Granule Organization Membrane Coat Vesicle Cargo Loading Vacuolar Transport Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Protein Transport Vesicle-mediated Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Intracellular Transport Protein Targeting To Vacuole Positive Regulation Of NK T Cell Differentiation Establishment Of Protein Localization Vesicle Cytoskeletal Trafficking Protein Localization To Lysosome Synaptic Vesicle Coating Axon Cytoplasm Establishment Of Protein Localization To Vacuole Axonal Transport Secretory Granule Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of NK T Cell Differentiation Cellular Localization Establishment Of Localization In Cell Axo-dendritic Transport Early Endosome Organelle Transport Along Microtubule Protein Localization To Vacuole Intracellular Protein Localization Establishment Of Vesicle Localization Vesicle Localization Lysosomal Transport Synaptic Vesicle Recycling Organelle Localization Golgi To Vacuole Transport Localization Within Membrane Transport Along Microtubule Golgi Apparatus Cytoskeleton-dependent Intracellular Transport Protein Targeting Protein Localization To Organelle Protein Localization To Cell Surface Protein Targeting To Lysosome	Synaptic Vesicle Coating Clathrin-coated Vesicle Cargo Loading, AP-3-mediated AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Synaptic Vesicle Recycling Membrane Coat Cellular Localization Vesicle Cargo Loading Synaptic Vesicle Transport Vesicle Coating Vacuolar Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Zinc Ion Import Into Lysosome Vesicle Cytoskeletal Trafficking Intracellular Transport Axon Cytoplasm Axonal Transport Establishment Of Protein Localization Vacuolar Transmembrane Transport Axo-dendritic Transport Organelle Transport Along Microtubule Vesicle Organization Zinc Ion Import Into Organelle Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Lysosomal Transport Melanosome Assembly Intracellular Membrane-bounded Organelle Golgi To Vacuole Transport Protein Transport Platelet Dense Granule Organization Transport Along Microtubule Intracellular Protein Transport Zinc Ion Transmembrane Transport Vesicle-mediated Transport Zinc Ion Transport Cytoskeleton-dependent Intracellular Transport Protein Targeting Microtubule-based Transport Melanosome Organization Pigment Granule Organization SH2 Domain Binding Establishment Of Organelle Localization Golgi Vesicle Transport Protein Targeting To Vacuole Protein Localization To Lysosome Regulation Of Lipid Catabolic Process Early Endosome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?