KIFC3 and GMCL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIFC3	GMCL1
Description		kinesin family member C3	germ cell-less 1, spermatogenesis associated
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Cytoskeleton Kinesin Complex Microtubule Adherens Junction Zonula Adherens Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome Anchoring Junction	Nucleus Nuclear Matrix
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Microtubule-based Process Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion	Germ Cell Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 28416818 29892015 30061737) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)
Interacting Genes		213 interacting genes: ABI2 ABI3 AIRIM ANKRD23 ANXA13 APP APPL2 ARNT2 ATF2 AXIN2 BARD1 BCL6 BEGAIN BFSP1 BYSL CARD9 CATSPERT CBFA2T2 CBX8 CBY2 CCDC102B CCDC136 CCDC146 CCDC187 CCDC198 CCDC28A CCDC33 CCHCR1 CCND3 CDC37 CDK18 CDKN1A CDR2 CEP55 CEP57L1 CLIP4 COG3 COG7 CREB5 CWF19L2 CYTH4 DCTN2 DCX DEUP1 DISC1 DSCAM DTNBP1 EIF3D ENKD1 ESRRG EXOC5 EXOC7 EXOC8 FAM124A FAM161A FAM90A1 FANCL FBXO7 FCHSD2 FEM1A FLYWCH1 FOSL1 GADD45GIP1 GEM GIGYF1 GMCL1 GOLGA1 GOLGA2 GORASP2 HAUS1 HMG20A HOMEZ HSBP1 HSF2BP ICA1L IGFN1 IHO1 IKZF3 IL16 IQUB ITGB3BP KANK2 KANSL1 KDM1A KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT3 KRT31 KRT32 KRT35 KRT38 KRT4 KRT40 KRT5 KRT6A KRT6B KRT6C KRT75 KRT76 KRT8 KRTAP19-5 KRTAP19-6 LBX1 LENG1 LIN37 LNX1 LZTS1 LZTS2 MBD3L1 MCC MCM7 MED4 MFAP1 MID2 MKRN3 MOS MRFAP1 MTUS2 MYO15B NAB2 NDC80 NDEL1 NEBL NECAB2 NEDD4 NEDD4L NEFL NSMF NUP62 PFDN6 PHC2 PIAS2 PIBF1 PIN1 PNMA5 PPP1R13B PRDM6 PRKAA2 PRPF18 PRPF31 PRPH PSMB1 RABIF RAD51D RAD54L2 RBM41 RSPH14 RUNX1T1 SCEL SCNM1 SCOC SHISA6 SIAH1 SMARCE1 SNAP29 SORBS3 SOX30 SOX5 SPATA2 SPATC1L SSX2IP STMN3 STX11 STX1A SVIL SYCE1 SYCE2 SYT6 SYTL4 TASOR2 TBC1D22B TCEANC TFIP11 TLE5 TNIP1 TNNI1 TPM3 TRAF2 TRIM14 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSGA10IP TSR2 UBC USH1G USP2 VIM VPS52 WASF3 ZBED1 ZBTB16 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF250 ZNF417 ZNF446 ZNF572 ZNF655 ZNF688 ZNF774 ZNF785 ZNF835 ZRANB1	98 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL CCDC13 CCDC25 CDC37 CFAP298 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KLHL20 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 SPATA31J1 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250
Entrez ID		3801	64395
HPRD ID		05171	13587
Ensembl ID		ENSG00000140859	ENSG00000087338
Uniprot IDs		B7Z5U4 B7Z808 B7Z896 F5H3M2 H3BMZ5 Q9BVG8	Q53SE7 Q96IK5
PDB IDs		5WDE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Structural Molecule Activity Nucleus Keratinization Centrosome Organelle Localization Microtubule-based Process Microtubule Organizing Center Epithelial Cell Differentiation Positive Regulation Of Actin Nucleation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Differentiation Hepatocyte Apoptotic Process Microtubule Cytoskeleton Organization Flemming Body Cytosol Regulation Of Transcription By RNA Polymerase II Chromosome Localization Epidermis Development Metaphase Chromosome Alignment Cellular Developmental Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Zinc Ion Binding Regulation Of Neuron Projection Development Post-translational Protein Modification Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Protein Ligase Activity Intermediate Filament Polymerization Or Depolymerization Vesicle Tethering Involved In Exocytosis Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Neurofilament Cytoskeleton Organization Scaffold Protein Binding Negative Regulation Of DNA-templated Transcription Developmental Process Epithelial Cell Apoptotic Process	Protein Binding Positive Regulation Of Viral Life Cycle Ubiquitin Protein Ligase Activity PML Body Protein Modification Process Regulation Of Viral Process Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Suppression Of Viral Release By Host Regulation Of Viral Transcription Negative Regulation Of Viral Transcription Transcription Factor Binding Protein Sumoylation Cytoplasm Post-translational Protein Modification Small Protein Activating Enzyme Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Process Modification-dependent Protein Catabolic Process
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