KIFC3 and KRT31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIFC3	KRT31
Description		kinesin family member C3	keratin 31
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Cytoskeleton Kinesin Complex Microtubule Adherens Junction Zonula Adherens Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome Anchoring Junction	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Identical Protein Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Microtubule-based Process Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Brown vs. black hair color ( 30531825)
Interacting Genes		213 interacting genes: ABI2 ABI3 AIRIM ANKRD23 ANXA13 APP APPL2 ARNT2 ATF2 AXIN2 BARD1 BCL6 BEGAIN BFSP1 BYSL CARD9 CATSPERT CBFA2T2 CBX8 CBY2 CCDC102B CCDC136 CCDC146 CCDC187 CCDC198 CCDC28A CCDC33 CCHCR1 CCND3 CDC37 CDK18 CDKN1A CDR2 CEP55 CEP57L1 CLIP4 COG3 COG7 CREB5 CWF19L2 CYTH4 DCTN2 DCX DEUP1 DISC1 DSCAM DTNBP1 EIF3D ENKD1 ESRRG EXOC5 EXOC7 EXOC8 FAM124A FAM161A FAM90A1 FANCL FBXO7 FCHSD2 FEM1A FLYWCH1 FOSL1 GADD45GIP1 GEM GIGYF1 GMCL1 GOLGA1 GOLGA2 GORASP2 HAUS1 HMG20A HOMEZ HSBP1 HSF2BP ICA1L IGFN1 IHO1 IKZF3 IL16 IQUB ITGB3BP KANK2 KANSL1 KDM1A KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT3 KRT31 KRT32 KRT35 KRT38 KRT4 KRT40 KRT5 KRT6A KRT6B KRT6C KRT75 KRT76 KRT8 KRTAP19-5 KRTAP19-6 LBX1 LENG1 LIN37 LNX1 LZTS1 LZTS2 MBD3L1 MCC MCM7 MED4 MFAP1 MID2 MKRN3 MOS MRFAP1 MTUS2 MYO15B NAB2 NDC80 NDEL1 NEBL NECAB2 NEDD4 NEDD4L NEFL NSMF NUP62 PFDN6 PHC2 PIAS2 PIBF1 PIN1 PNMA5 PPP1R13B PRDM6 PRKAA2 PRPF18 PRPF31 PRPH PSMB1 RABIF RAD51D RAD54L2 RBM41 RSPH14 RUNX1T1 SCEL SCNM1 SCOC SHISA6 SIAH1 SMARCE1 SNAP29 SORBS3 SOX30 SOX5 SPATA2 SPATC1L SSX2IP STMN3 STX11 STX1A SVIL SYCE1 SYCE2 SYT6 SYTL4 TASOR2 TBC1D22B TCEANC TFIP11 TLE5 TNIP1 TNNI1 TPM3 TRAF2 TRIM14 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSGA10IP TSR2 UBC USH1G USP2 VIM VPS52 WASF3 ZBED1 ZBTB16 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF250 ZNF417 ZNF446 ZNF572 ZNF655 ZNF688 ZNF774 ZNF785 ZNF835 ZRANB1	397 interacting genes: A1CF ABI2 ABI3 ABL1 ACTR10 AGR2 AGXT AIMP2 AIRIM AKR7A3 ALDH3B1 ALG13 AMOT AMOTL2 ANKRD36BP1 ANKS1A AQP1 AQP5 ARHGAP35 ARID3A ARMC7 ARSJ ASMTL ASPSCR1 ATG9A ATN1 ATXN7L1 ATXN7L2 AVPI1 B4GALT7 BAD BAG4 BCAS2 BEX1 BEX2 BFSP2 BHLHA9 BRME1 BTC BYSL C19orf73 C1orf216 C3 CA6 CARD9 CATIP CATSPER1 CATSPERT CBX8 CCDC112 CCDC116 CCDC120 CCDC146 CCDC17 CCDC187 CCDC196 CCDC198 CCDC93 CCER1 CCHCR1 CCNC CD33 CDC20B CDK13 CDK18 CDKN1A CDKN2C CDR2L CEP55 CEP57 CEP57L1 CEP70 CFAP206 CFAP53 CFAP90 CFTR CHCHD2 CHRNG CIMIP4 CLCNKA CLDN19 CLDN2 CLEC18A CNNM3 CNTF COA5 COMT COX5A COX5B CPSF7 CRACR2A CREB5 CRH CTSG CXCL16 CYSRT1 DEF6 DGCR6L DHX37 DHX57 DMRT3 DOCK2 DTNB EIF4E2 EIF4ENIF1 EIF4G1 ENKD1 EPDR1 ESS2 EXOC8 EXOSC5 EXOSC7 FADS2 FAM110A FAM124B FAM50B FAM74A4 FAM90A1 FARS2 FBF1 FBXW5 FGF16 FKBP1B FOXB1 FRS3 GAD1 GADD45GIP1 GARIN6 GEM GFAP GFOD1 GLRX3 GNAI2 GNE GNG10 GNG5 GOLGA6L2 GPS2 GRN GSTP1 HAPLN2 HAUS1 HBA1 HBA2 HBZ HCK HDAC4 HGS HNRNPLL HOXA1 HOXB5 HOXC8 HS6ST1 HSD3B7 HSF4 HSPA12B HSPD1 HYAL2 ICAM4 IL16 INPP5D INPP5K INSR ITGB2 ITGB4 ITGB5 JOSD1 KANK2 KCTD9 KDM1A KIAA1217 KIFC3 KLC1 KLC4 KLHL38 KLK8 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 KRTAP4-12 KRTAP5-6 KRTAP9-2 KRTAP9-3 LATS1 LCE1B LCE3C LCE3D LCE3E LCE4A LENG1 LIF LIN37 LINC00526 LMF2 LMNTD2 LMO3 LMO4 LONRF1 LRRC41 MAB21L2 MAP3K7CL MAPKBP1 MARK4 MAZ MID2 MOS MRPL40 MRPL44 MRPS11 MSRB3 MTA1 MXD3 MXI1 MYO15B MYOM1 NAV1 NAXD NEK6 NODAL NPBWR2 NTAQ1 NUDT16L1 NUFIP2 NXF1 OTUB2 OTX1 P2RX7 P3H3 PATL1 PBX3 PDE4DIP PDGFRB PGAP6 PGLS PHC2 PHLDA1 PIN1 PKN1 PKN3 PKP2 PLEKHN1 POLDIP3 POU4F2 POU4F3 PPP1R18 PRF1 PRKAA2 PRKAB2 PRPF18 PRPF31 PRPF6 PRPH PRR19 PRR3 PRR35 PSMA1 PSMB1 PSMC5 PSMG2 PSPC1 PTGER3 PTPMT1 R3HDM2 RAB33A RADIL RAMAC RBFOX2 RBM15 RBM22 RBM7 RCOR3 RHPN1 RIBC1 RPL5 RPS19BP1 RPUSD3 RSPH14 RTP5 SAMD11 SAXO4 SCNM1 SEC14L4 SEMA4C SF1 SFPQ SHC3 SHFL SHISA6 SIRPA SLAIN1 SLC15A3 SLC23A1 SLC25A42 SLC25A6 SLIRP SMARCD1 SMARCE1 SMCP SMG9 SNAI1 SNRNP25 SNRPB SNRPC SNW1 SPATA24 SPATA31J1 SPG21 SPON2 SPRING1 SPRY1 SRSF2 SSX2IP STK16 SUV39H1 TACO1 TAPBPL TCEANC TEAD4 TEPSIN TEX28 TFAP2D THAP7 TIAL1 TLE5 TMEM106C TMEM174 TMEM231 TMSB4X TRAF4 TRIML2 TROAP TSEN54 TSG101 TSHZ3 TSNAX TTC23 TTC9C TXLNA TXNL4A TYK2 UACA UBASH3A UNKL USHBP1 USP2 UTP14A UTP23 UXT VASN VPS9D1 WDR25 WFDC6 ZC3H8 ZDHHC1 ZFHX3 ZFYVE21 ZGPAT ZIC1 ZMAT5 ZNF124 ZNF148 ZNF20 ZNF250 ZNF414 ZNF417 ZNF446 ZNF564 ZNF569 ZNF572 ZNF587 ZNF648 ZNF688 ZNF69 ZNF835 ZNRF2P1
Entrez ID		3801	3881
HPRD ID		05171	03047
Ensembl ID		ENSG00000140859	ENSG00000094796
Uniprot IDs		B7Z5U4 B7Z808 B7Z896 F5H3M2 H3BMZ5 Q9BVG8	Q15323
PDB IDs		5WDE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Structural Molecule Activity Nucleus Keratinization Centrosome Organelle Localization Microtubule-based Process Microtubule Organizing Center Epithelial Cell Differentiation Positive Regulation Of Actin Nucleation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Differentiation Hepatocyte Apoptotic Process Microtubule Cytoskeleton Organization Flemming Body Cytosol Regulation Of Transcription By RNA Polymerase II Chromosome Localization Epidermis Development Metaphase Chromosome Alignment Cellular Developmental Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Zinc Ion Binding Regulation Of Neuron Projection Development Post-translational Protein Modification Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Protein Ligase Activity Intermediate Filament Polymerization Or Depolymerization Vesicle Tethering Involved In Exocytosis Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Neurofilament Cytoskeleton Organization Scaffold Protein Binding Negative Regulation Of DNA-templated Transcription Developmental Process Epithelial Cell Apoptotic Process	Protein Binding Keratinization Intermediate Filament Organization Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Epidermis Development Organelle Organization Carbon Dioxide Transport Spliceosomal Complex MRNA Processing Cytoskeleton Nuclear Speck Positive Regulation Of Urine Volume MRNA Metabolic Process Nitric Oxide Transport Nucleus RNA Processing
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