KIFC3 and TRIM23

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KIFC3	TRIM23
Description		kinesin family member C3	tripartite motif containing 23
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Cytoskeleton Kinesin Complex Microtubule Adherens Junction Zonula Adherens Microtubule Cytoskeleton Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome Anchoring Junction	Golgi Membrane Nucleus Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Endomembrane System Membrane
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Identical Protein Binding	Nucleotide Binding GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Transferase Activity GDP Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Microtubule-based Process Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion	Immune System Process Intracellular Protein Transport Positive Regulation Of Autophagy Vesicle-mediated Transport Protein Ubiquitination Innate Immune Response
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		213 interacting genes: ABI2 ABI3 AIRIM ANKRD23 ANXA13 APP APPL2 ARNT2 ATF2 AXIN2 BARD1 BCL6 BEGAIN BFSP1 BYSL CARD9 CATSPERT CBFA2T2 CBX8 CBY2 CCDC102B CCDC136 CCDC146 CCDC187 CCDC198 CCDC28A CCDC33 CCHCR1 CCND3 CDC37 CDK18 CDKN1A CDR2 CEP55 CEP57L1 CLIP4 COG3 COG7 CREB5 CWF19L2 CYTH4 DCTN2 DCX DEUP1 DISC1 DSCAM DTNBP1 EIF3D ENKD1 ESRRG EXOC5 EXOC7 EXOC8 FAM124A FAM161A FAM90A1 FANCL FBXO7 FCHSD2 FEM1A FLYWCH1 FOSL1 GADD45GIP1 GEM GIGYF1 GMCL1 GOLGA1 GOLGA2 GORASP2 HAUS1 HMG20A HOMEZ HSBP1 HSF2BP ICA1L IGFN1 IHO1 IKZF3 IL16 IQUB ITGB3BP KANK2 KANSL1 KDM1A KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT3 KRT31 KRT32 KRT35 KRT38 KRT4 KRT40 KRT5 KRT6A KRT6B KRT6C KRT75 KRT76 KRT8 KRTAP19-5 KRTAP19-6 LBX1 LENG1 LIN37 LNX1 LZTS1 LZTS2 MBD3L1 MCC MCM7 MED4 MFAP1 MID2 MKRN3 MOS MRFAP1 MTUS2 MYO15B NAB2 NDC80 NDEL1 NEBL NECAB2 NEDD4 NEDD4L NEFL NSMF NUP62 PFDN6 PHC2 PIAS2 PIBF1 PIN1 PNMA5 PPP1R13B PRDM6 PRKAA2 PRPF18 PRPF31 PRPH PSMB1 RABIF RAD51D RAD54L2 RBM41 RSPH14 RUNX1T1 SCEL SCNM1 SCOC SHISA6 SIAH1 SMARCE1 SNAP29 SORBS3 SOX30 SOX5 SPATA2 SPATC1L SSX2IP STMN3 STX11 STX1A SVIL SYCE1 SYCE2 SYT6 SYTL4 TASOR2 TBC1D22B TCEANC TFIP11 TLE5 TNIP1 TNNI1 TPM3 TRAF2 TRIM14 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSGA10IP TSR2 UBC USH1G USP2 VIM VPS52 WASF3 ZBED1 ZBTB16 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF250 ZNF417 ZNF446 ZNF572 ZNF655 ZNF688 ZNF774 ZNF785 ZNF835 ZRANB1	219 interacting genes: ACTN4 AKTIP ANKRD36BP1 ANKRD55 ANO1 AP3M1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B BICRAL BRME1 C8orf33 CARD9 CATSPERT CBX8 CCDC13 CCDC146 CCDC25 CCDC33 CDC20B CDC73 CDR2 CFAP53 CHP1P2 CIMIP4 COX5B CPNE7 CREB5 CSRP2 CWF19L2 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EHHADH EIF3D ENKD1 EPN2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GGA3 GLIDR GMCL2 GPANK1 GPKOW HAPLN2 HAUS1 HGS HNRNPLL HOXB5 HSPB7 IL16 IQCE IQUB JOSD1 JRK KAT5 KIFC3 KLHL42 KRT6A KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LMO3 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MSRB3 MTFR2 MYEF2 MYOM1 MYOZ1 NAB2 NEDD9 NEK6 NFU1 NOXA1 NTAQ1 NUDT21 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 PLEKHA2 POLI POLL POM121 PPIL2 PPP1R15B PPP1R18 PRPF18 PRPF31 PSMA1 PSMB1 RAD18 RAMAC RCAN3 RIBC1 RIBC2 RIN1 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 RUFY1 SCNM1 SF1 SH2D4A SIAH1 SIRPA SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SNRPB2 SNW1 SORBS3 SPG21 SUMO1P1 TACO1 TASOR2 TBC1D22B TCEA2 TCEANC TEPSIN TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TRIM55 TRIM63 TROAP TSEN54 TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 UBQLN1 USP2 USP20 USP21 UTP23 VGLL1 WDR25 WHR1 ZBTB16 ZBTB4 ZC2HC1C ZFAND2A ZNF20 ZNF250 ZNF408 ZNF417 ZNF474 ZNF564 ZNF581 ZNF587 ZNF688 ZNF835
Entrez ID		3801	373
HPRD ID		05171	03449
Ensembl ID		ENSG00000140859	ENSG00000113595
Uniprot IDs		B7Z5U4 B7Z808 B7Z896 F5H3M2 H3BMZ5 Q9BVG8	P36406
PDB IDs		5WDE	5VZV 5VZW
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Cytoskeleton Structural Constituent Of Cytoskeleton Identical Protein Binding Structural Molecule Activity Nucleus Keratinization Centrosome Organelle Localization Microtubule-based Process Microtubule Organizing Center Epithelial Cell Differentiation Positive Regulation Of Actin Nucleation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Differentiation Hepatocyte Apoptotic Process Microtubule Cytoskeleton Organization Flemming Body Cytosol Regulation Of Transcription By RNA Polymerase II Chromosome Localization Epidermis Development Metaphase Chromosome Alignment Cellular Developmental Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Zinc Ion Binding Regulation Of Neuron Projection Development Post-translational Protein Modification Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Protein Ligase Activity Intermediate Filament Polymerization Or Depolymerization Vesicle Tethering Involved In Exocytosis Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Neurofilament Cytoskeleton Organization Scaffold Protein Binding Negative Regulation Of DNA-templated Transcription Developmental Process Epithelial Cell Apoptotic Process	Protein Binding Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Ubiquitination Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Nucleus Ubiquitin Protein Ligase Activity Proteolysis Involved In Protein Catabolic Process Protein K63-linked Ubiquitination Zinc Ion Binding Protein Modification Process Ubiquitin-protein Transferase Activator Activity Macromolecule Catabolic Process Protein Monoubiquitination Proteolysis Ubiquitin Protein Ligase Binding Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin Binding SUMO Transferase Activity Spliceosomal Complex Nuclear Speck Proteasomal Protein Catabolic Process Macromolecule Metabolic Process Establishment Of Protein Localization To Vacuole MRNA Processing Spindle Pole Identical Protein Binding Protein Metabolic Process Metal Ion Binding SnRNP Binding Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Striated Muscle Myosin Thick Filament Cytoplasm Protein Sumoylation
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