CXCR4 and PTPN11

  • Number of citations of the paper that reports this interaction (PMID 11157475)
  • 10
  • Data Source:
  • HPRD (in vivo)

CXCR4

PTPN11

Gene Name chemokine (C-X-C motif) receptor 4 protein tyrosine phosphatase, non-receptor type 11
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 32 interactors: ADRBK2 ARRB2 ATP13A2 CCR5 CD4 CTSG CXCL12 DPP4 ELANE GNA13 GNAI1 HLA-C HSPA8 ITCH JAK1 JAK2 JAK3 MYBL2 MYH9 PTK2 PTPN11 PTPN6 PTPRC SDC4 SOCS1 SOCS3 STAT1 STAT2 STAT3 STAT5B USP14 VAV1 114 interactors: ACTN4 ARHGAP1 AXL BCR BDKRB2 BTLA C6orf25 CAT CAV1 CBL CCKBR CD33 CDH5 CEACAM1 CHUK CRKL CSF2RB CSF3R CTLA4 CXCR4 DAB1 DDR1 EGFR EPHA2 EPOR ERBB2 FCRL3 FLT1 FLT4 FRS2 FRS3 FYN GAB1 GAB2 GAB3 GHR GRB2 GRIN2B HNRNPU IFNAR1 IFNGR1 IGF1R IL4R IL6ST INPP5D INSR IRS1 IRS2 IRS4 JAK1 JAK2 KDR KIR2DL5A KIT KLRC1 LAIR1 LCK LEPR LIFR LILRB4 MAP3K4 MAP3K5 MAPK3 MET MPL MPZL1 MS4A2 MVP NEDD9 NTRK1 NTRK2 PAG1 PDGFRA PDGFRB PECAM1 PIK3CG PIK3R1 PILRA PILRB PLCG1 PRKCA PRKCB PRKCH PRLR PTK2 PTK2B PTPN6 PXN RET ROS1 RPIA SELE SHC1 SIGLEC11 SIGLEC12 SIGLEC7 SIRPA SIT1 SLAMF1 SLAMF6 SOCS3 SOS1 SPRY2 SRC STAT1 STAT3 STAT5A STAT5B SYNCRIP TEK TIE1 TNFRSF1A TREML1 TRIM32
Entrez ID 7852 5781
HPRD ID 01217 01470
Ensembl ID ENSG00000121966 ENSG00000179295
Uniprot IDs P61073 Q06124
PDB IDs 2K03 2K04 2K05 3ODU 3OE0 3OE6 3OE8 3OE9 2SHP 3B7O 3MOW 3O5X 3TKZ 3TL0 4DGP 4DGX 4GWF 4H1O 4H34 4JE4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Difference) ?
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Intersection) ?