CXCR4 and JAK1

  • Number of citations of the paper that reports this interaction (PMID 12163560)
  • 16
  • Data Source:
  • HPRD (in vivo)

CXCR4

JAK1

Gene Name chemokine (C-X-C motif) receptor 4 Janus kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 32 interactors: ADRBK2 ARRB2 ATP13A2 CCR5 CD4 CTSG CXCL12 DPP4 ELANE GNA13 GNAI1 HLA-C HSPA8 ITCH JAK1 JAK2 JAK3 MYBL2 MYH9 PTK2 PTPN11 PTPN6 PTPRC SDC4 SOCS1 SOCS3 STAT1 STAT2 STAT3 STAT5B USP14 VAV1 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2
Entrez ID 7852 3716
HPRD ID 01217 00992
Ensembl ID ENSG00000121966 ENSG00000162434
Uniprot IDs P61073 P23458
PDB IDs 2K03 2K04 2K05 3ODU 3OE0 3OE6 3OE8 3OE9 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01
Enriched GO Terms of Interacting Partners?
Tagcloud ?
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Difference) ?
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Intersection) ?
responsiveness