Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ITGA6 and BIN1
Number of citations of the paper that reports this interaction (PMID
10094488
)
9
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ITGA6
BIN1
Gene Name
integrin, alpha 6
bridging integrator 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Basement Membrane
Plasma Membrane
Cell-cell Adherens Junction
Focal Adhesion
External Side Of Plasma Membrane
Basal Plasma Membrane
Cell Surface
Hemidesmosome
Filopodium
Integrin Alpha6-beta4 Complex
Nucleus
Cytoplasm
Synaptic Vesicle
Actin Cytoskeleton
Membrane
Z Disc
T-tubule
Axon
I Band
Node Of Ranvier
Axon Initial Segment
Varicosity
Axon Terminus
Cerebellar Mossy Fiber
Lipid Tube
Molecular Function
Integrin Binding
Protein Binding
Laminin Binding
Metal Ion Binding
Protein Binding
Protein Complex Binding
Identical Protein Binding
Protein Heterodimerization Activity
Tau Protein Binding
GTPase Binding
RNA Polymerase Binding
Biological Process
Cell-substrate Junction Assembly
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Blood Coagulation
Ectodermal Cell Differentiation
Positive Regulation Of Cell-substrate Adhesion
Single Organismal Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell-substrate Adhesion
Cellular Response To Extracellular Stimulus
Cell Adhesion Mediated By Integrin
Cell Junction Assembly
Nail Development
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Skin Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Filopodium Assembly
Digestive Tract Development
Brown Fat Cell Differentiation
Leukocyte Migration
Cellular Response To Organic Cyclic Compound
Renal System Development
Amelogenesis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Endocytosis
Cell Proliferation
Viral Process
Muscle Cell Differentiation
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Astrocyte Differentiation
Lipid Tube Assembly
Regulation Of Cell Cycle Arrest
Pathways
Cell junction organization
Syndecan interactions
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Integrin cell surface interactions
Non-integrin membrane-ECM interactions
Assembly of collagen fibrils and other multimeric structures
Basigin interactions
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Alzheimer's disease biomarkers (
23419831
)
Prostate cancer (
19767753
)
Alzheimer's disease (
22832961
21460840
21627779
22005930
)
Alzheimer's disease (late onset) (
21460841
21390209
)
Protein-Protein Interactions
21 interactors:
ADAM9
APP
BIN1
CALM1
CANX
CD151
CD36
CD63
CD82
COL17A1
GIPC1
GRB2
ITGB1
ITGB4
PCSK5
PLEC
PRKCD
PXN
RABIF
RPSA
TSPAN4
36 interactors:
ABL1
AMPH
AP2A1
AP2A2
APP
ASAP2
ATXN2
CUX1
DLGAP4
DNM1
DNM2
FBP1
ITGA1
ITGA3
ITGA6
MAP4K3
MBNL1
MYC
PLD1
PLD2
PTK2
RAP1A
RFX3
RIN2
RIN3
SH3GL2
SH3GLB1
SNX4
SOS1
SOS2
SYN1
SYNJ1
TP73
UBC
XRCC4
ZBTB3
Entrez ID
3655
274
HPRD ID
00945
03150
Ensembl ID
ENSG00000091409
ENSG00000136717
Uniprot IDs
P23229
B7Z6Y2
O00499
Q9BTH3
PDB IDs
1MUZ
1MV0
1MV3
2FIC
2RMY
2RND
Enriched GO Terms of Interacting Partners
?
Hemidesmosome Assembly
Cell-substrate Junction Assembly
Cell Activation
Cell-matrix Adhesion
Cell Junction Assembly
Cell Adhesion
Platelet Activation
Cell-substrate Adhesion
Extracellular Matrix Organization
Extracellular Structure Organization
Blood Coagulation
Hemostasis
Response To Wounding
Cellular Component Assembly
Secretion By Cell
Regulation Of Body Fluid Levels
Platelet Degranulation
Response To Growth Factor
Wound Healing
Secretion
Positive Regulation Of Endocytosis
Positive Regulation Of Transport
Integrin-mediated Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Regulation Of MAPK Cascade
Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
ERBB Signaling Pathway
Endocytosis
Vesicle-mediated Transport
Establishment Of Protein Localization
Regulation Of Endocytosis
Regulation Of Phosphorus Metabolic Process
Regulation Of Cellular Amino Acid Metabolic Process
Movement Of Cell Or Subcellular Component
Establishment Of Localization In Cell
Regulation Of Protein Phosphorylation
Cell-cell Adhesion Mediated By Integrin
Response To Oxidative Stress
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Transport
Positive Regulation Of Metabolic Process
Regulation Of Signal Transduction
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Signaling
Endocytosis
Generation Of Neurons
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Projection Organization
Regulation Of ERBB Signaling Pathway
Neurogenesis
Neuron Projection Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Regulation Of Signal Transduction
Axon Guidance
Neuron Differentiation
Neuron Development
Nervous System Development
Vesicle-mediated Transport
Chemotaxis
Signaling
Neuron Projection Development
Locomotion
Cell Communication
Anatomical Structure Morphogenesis
Cell Morphogenesis
Axonogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Axon Development
Negative Regulation Of Signaling
Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Cellular Process
Cell Development
Positive Regulation Of Catalytic Activity
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
System Development
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Metabolic Process
Cell Morphogenesis Involved In Differentiation
Regulation Of Catalytic Activity
Regulation Of Intracellular Signal Transduction
Movement Of Cell Or Subcellular Component
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Positive Regulation Of Apoptotic Process
Blood Coagulation
Tagcloud
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Difference)
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Intersection)
?