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ITGA6 and CD36
Number of citations of the paper that reports this interaction (PMID
11238109
)
24
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
ITGA6
CD36
Gene Name
integrin, alpha 6
CD36 molecule (thrombospondin receptor)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Basement Membrane
Plasma Membrane
Cell-cell Adherens Junction
Focal Adhesion
External Side Of Plasma Membrane
Basal Plasma Membrane
Cell Surface
Hemidesmosome
Filopodium
Integrin Alpha6-beta4 Complex
Extracellular Space
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Membrane
Endocytic Vesicle Membrane
Platelet Alpha Granule Membrane
Membrane Raft
Phagocytic Vesicle
Molecular Function
Integrin Binding
Protein Binding
Laminin Binding
Metal Ion Binding
Low-density Lipoprotein Receptor Activity
High-density Lipoprotein Particle Binding
Lipid Binding
Low-density Lipoprotein Particle Binding
Transforming Growth Factor Beta Binding
Thrombospondin Receptor Activity
Lipoteichoic Acid Receptor Activity
Lipoprotein Particle Binding
Biological Process
Cell-substrate Junction Assembly
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Blood Coagulation
Ectodermal Cell Differentiation
Positive Regulation Of Cell-substrate Adhesion
Single Organismal Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell-substrate Adhesion
Cellular Response To Extracellular Stimulus
Cell Adhesion Mediated By Integrin
Cell Junction Assembly
Nail Development
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Skin Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Filopodium Assembly
Digestive Tract Development
Brown Fat Cell Differentiation
Leukocyte Migration
Cellular Response To Organic Cyclic Compound
Renal System Development
Amelogenesis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cell-matrix Adhesion
Toll-like Receptor Signaling Pathway
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Platelet Degranulation
MyD88-dependent Toll-like Receptor Signaling Pathway
Lipid Metabolic Process
Receptor-mediated Endocytosis
Phagocytosis, Recognition
Cell Adhesion
Cell Surface Receptor Signaling Pathway
Nitric Oxide Mediated Signal Transduction
Blood Coagulation
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Cholesterol Storage
Plasma Membrane Long-chain Fatty Acid Transport
Lipid Storage
CGMP-mediated Signaling
Platelet Activation
Positive Regulation Of Blood Coagulation
Cholesterol Transport
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Plasma Lipoprotein Particle Clearance
Low-density Lipoprotein Particle Clearance
Response To Stilbenoid
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Lipoprotein Transport
Negative Regulation Of Transcription Factor Import Into Nucleus
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Apoptotic Cell Clearance
Positive Regulation Of MAPK Cascade
Negative Regulation Of Growth Of Symbiont In Host
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Long-chain Fatty Acid Import
Innate Immune Response
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Defense Response To Gram-positive Bacterium
Low-density Lipoprotein Particle Mediated Signaling
Positive Regulation Of Phagocytosis, Engulfment
Positive Regulation Of Macrophage Cytokine Production
Cellular Response To Bacterial Lipopeptide
Cellular Response To Lipopolysaccharide
Cellular Response To Lipoteichoic Acid
Cellular Response To Hydroperoxide
Regulation Of Removal Of Superoxide Radicals
Positive Regulation Of Blood Microparticle Formation
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Cell junction organization
Syndecan interactions
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Integrin cell surface interactions
Non-integrin membrane-ECM interactions
Assembly of collagen fibrils and other multimeric structures
Basigin interactions
Cell surface interactions at the vascular wall
PPARA activates gene expression
Metabolism of lipids and lipoproteins
Platelet degranulation
Toll Like Receptor TLR6:TLR2 Cascade
Activated TLR4 signalling
Toll Like Receptor TLR1:TLR2 Cascade
Response to elevated platelet cytosolic Ca2+
Transcriptional regulation of white adipocyte differentiation
MyD88:Mal cascade initiated on plasma membrane
Class I MHC mediated antigen processing & presentation
Innate Immune System
Fatty acid, triacylglycerol, and ketone body metabolism
Toll Like Receptor 2 (TLR2) Cascade
Toll-Like Receptors Cascades
Toll Like Receptor 4 (TLR4) Cascade
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Platelet activation, signaling and aggregation
Scavenging by Class B Receptors
Antigen processing-Cross presentation
Cross-presentation of particulate exogenous antigens (phagosomes)
Adaptive Immune System
Drugs
Diseases
GWAS
Alzheimer's disease biomarkers (
23419831
)
Prostate cancer (
19767753
)
HDL cholesterol (
23726366
)
Left ventricular mass (
19454037
)
Mean platelet volume (
22423221
)
Response to fenofibrate (
22890011
)
Protein-Protein Interactions
21 interactors:
ADAM9
APP
BIN1
CALM1
CANX
CD151
CD36
CD63
CD82
COL17A1
GIPC1
GRB2
ITGB1
ITGB4
PCSK5
PLEC
PRKCD
PXN
RABIF
RPSA
TSPAN4
18 interactors:
APP
CD9
CHRD
COL1A1
COL1A2
FYN
HSD11B1
ITGA2B
ITGA6
ITGB1
ITGB3
LDLR
LYN
MATK
SRC
THBS1
VLDLR
YES1
Entrez ID
3655
948
HPRD ID
00945
01430
Ensembl ID
ENSG00000091409
ENSG00000135218
Uniprot IDs
P23229
A4D1B1
P16671
PDB IDs
Enriched GO Terms of Interacting Partners
?
Hemidesmosome Assembly
Cell-substrate Junction Assembly
Cell Activation
Cell-matrix Adhesion
Cell Junction Assembly
Cell Adhesion
Platelet Activation
Cell-substrate Adhesion
Extracellular Matrix Organization
Extracellular Structure Organization
Blood Coagulation
Hemostasis
Response To Wounding
Cellular Component Assembly
Secretion By Cell
Regulation Of Body Fluid Levels
Platelet Degranulation
Response To Growth Factor
Wound Healing
Secretion
Positive Regulation Of Endocytosis
Positive Regulation Of Transport
Integrin-mediated Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Regulation Of MAPK Cascade
Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
ERBB Signaling Pathway
Endocytosis
Vesicle-mediated Transport
Establishment Of Protein Localization
Regulation Of Endocytosis
Regulation Of Phosphorus Metabolic Process
Regulation Of Cellular Amino Acid Metabolic Process
Movement Of Cell Or Subcellular Component
Establishment Of Localization In Cell
Regulation Of Protein Phosphorylation
Cell-cell Adhesion Mediated By Integrin
Response To Oxidative Stress
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Transport
Positive Regulation Of Metabolic Process
Regulation Of Signal Transduction
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Platelet Activation
Response To Wounding
Leukocyte Migration
Movement Of Cell Or Subcellular Component
Locomotion
Cell Activation
Anatomical Structure Morphogenesis
Vesicle-mediated Transport
Cell Migration
Cell Motility
Endocytosis
Platelet Degranulation
Anatomical Structure Development
Peptidyl-tyrosine Autophosphorylation
System Development
Positive Regulation Of Cell Adhesion
Extracellular Matrix Organization
Extracellular Structure Organization
Axon Guidance
Regulation Of Cell Adhesion
Developmental Process
Response To External Stimulus
Multicellular Organismal Development
Axonogenesis
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Cell Differentiation
Positive Regulation Of Cellular Component Movement
Response To Stress
Immune System Process
Axon Development
Positive Regulation Of Locomotion
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Cell Migration
Chemotaxis
Regulation Of Cell Motility
Neuron Projection Morphogenesis
Organ Development
Regulation Of Locomotion
Cell Surface Receptor Signaling Pathway
Regulation Of Cellular Component Movement
Cell Morphogenesis Involved In Differentiation
Integrin-mediated Signaling Pathway
Regulation Of Cell Proliferation
Response To Abiotic Stimulus
Cell Projection Organization
Tagcloud
?
benzidine
bfu
cd41
cd71
cfu
csf
cytokines
e2
epo
erythroid
erythropoiesis
erythropoietin
events
express
gata
glycophorin
gm
interestingly
late
leukemia
line
lineage
pas
progenitor
reagent
stages
strictly
transforming
understand
Tagcloud (Difference)
?
benzidine
bfu
cd41
cd71
cfu
csf
cytokines
e2
epo
erythroid
erythropoiesis
erythropoietin
events
express
gata
glycophorin
gm
interestingly
late
leukemia
line
lineage
pas
progenitor
reagent
stages
strictly
transforming
understand
Tagcloud (Intersection)
?