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ITGA6 and ITGB4
Number of citations of the paper that reports this interaction (PMID
9660880
)
35
Data Source:
HPRD
(in vivo)
ITGA6
ITGB4
Gene Name
integrin, alpha 6
integrin, beta 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Basement Membrane
Plasma Membrane
Cell-cell Adherens Junction
Focal Adhesion
External Side Of Plasma Membrane
Basal Plasma Membrane
Cell Surface
Hemidesmosome
Filopodium
Integrin Alpha6-beta4 Complex
Basement Membrane
Plasma Membrane
Integrin Complex
Basal Plasma Membrane
Cell Surface
Hemidesmosome
Cell Leading Edge
Receptor Complex
Extracellular Vesicular Exosome
Molecular Function
Integrin Binding
Protein Binding
Laminin Binding
Metal Ion Binding
G-protein Coupled Receptor Binding
Receptor Activity
Protein Binding
Biological Process
Cell-substrate Junction Assembly
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Blood Coagulation
Ectodermal Cell Differentiation
Positive Regulation Of Cell-substrate Adhesion
Single Organismal Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell-substrate Adhesion
Cellular Response To Extracellular Stimulus
Cell Adhesion Mediated By Integrin
Cell Junction Assembly
Nail Development
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Skin Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Filopodium Assembly
Digestive Tract Development
Brown Fat Cell Differentiation
Leukocyte Migration
Cellular Response To Organic Cyclic Compound
Renal System Development
Amelogenesis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Autophagy
Cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Response To Wounding
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell Junction Assembly
Nail Development
Skin Development
Filopodium Assembly
Mesodermal Cell Differentiation
Digestive Tract Development
Cell Motility
Renal System Development
Amelogenesis
Pathways
Cell junction organization
Syndecan interactions
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Integrin cell surface interactions
Non-integrin membrane-ECM interactions
Assembly of collagen fibrils and other multimeric structures
Basigin interactions
Cell surface interactions at the vascular wall
Cell junction organization
Syndecan interactions
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Non-integrin membrane-ECM interactions
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Alzheimer's disease biomarkers (
23419831
)
Prostate cancer (
19767753
)
Protein-Protein Interactions
21 interactors:
ADAM9
APP
BIN1
CALM1
CANX
CD151
CD36
CD63
CD82
COL17A1
GIPC1
GRB2
ITGB1
ITGB4
PCSK5
PLEC
PRKCD
PXN
RABIF
RPSA
TSPAN4
23 interactors:
ALOX12
ATXN1
CLCA1
CLCA2
COL17A1
DST
EIF6
ERBB2
ERBB2IP
FYN
GRB2
ITGA6
MET
PLEC
PRKCA
PRKCD
PTK2
SHC1
SREBF2
VIM
YES1
YWHAB
YWHAQ
Entrez ID
3655
3691
HPRD ID
00945
00946
Ensembl ID
ENSG00000091409
ENSG00000132470
Uniprot IDs
P23229
P16144
PDB IDs
1QG3
2YRZ
3F7P
3F7Q
3F7R
3FQ4
3FSO
3H6A
Enriched GO Terms of Interacting Partners
?
Hemidesmosome Assembly
Cell-substrate Junction Assembly
Cell Activation
Cell-matrix Adhesion
Cell Junction Assembly
Cell Adhesion
Platelet Activation
Cell-substrate Adhesion
Extracellular Matrix Organization
Extracellular Structure Organization
Blood Coagulation
Hemostasis
Response To Wounding
Cellular Component Assembly
Secretion By Cell
Regulation Of Body Fluid Levels
Platelet Degranulation
Response To Growth Factor
Wound Healing
Secretion
Positive Regulation Of Endocytosis
Positive Regulation Of Transport
Integrin-mediated Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Regulation Of MAPK Cascade
Protein Transport
Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
ERBB Signaling Pathway
Endocytosis
Vesicle-mediated Transport
Establishment Of Protein Localization
Regulation Of Endocytosis
Regulation Of Phosphorus Metabolic Process
Regulation Of Cellular Amino Acid Metabolic Process
Movement Of Cell Or Subcellular Component
Establishment Of Localization In Cell
Regulation Of Protein Phosphorylation
Cell-cell Adhesion Mediated By Integrin
Response To Oxidative Stress
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Transport
Positive Regulation Of Metabolic Process
Regulation Of Signal Transduction
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell-cell Adhesion
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Wounding
Cellular Response To Fibroblast Growth Factor Stimulus
Hemidesmosome Assembly
Response To Fibroblast Growth Factor
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Response To Growth Factor
Wound Healing
Regulation Of Cell Adhesion
Peptidyl-tyrosine Phosphorylation
Blood Coagulation
Hemostasis
Locomotion
Immune Response-regulating Signaling Pathway
Platelet Activation
Protein Autophosphorylation
Innate Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Chemotaxis
Axon Guidance
Leukocyte Migration
Cell Motility
Positive Regulation Of Signal Transduction
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Apoptotic Process
Cell-substrate Junction Assembly
Regulation Of Cell Activation
Programmed Cell Death
Cell Death
Death
Cellular Response To Peptide Hormone Stimulus
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cellular Response To Organic Substance
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of Platelet Aggregation
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud
?
bag1
bcl2l2
bctis
ccna2
comprehend
ctsb
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Difference)
?
bag1
bcl2l2
bctis
ccna2
comprehend
ctsb
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Intersection)
?