PTPN6 and IRS4

  • Number of citations of the paper that reports this interaction (PMID 12774026)
  • 6
  • Data Source:
  • HPRD (in vitro)

PTPN6

IRS4

Gene Name protein tyrosine phosphatase, non-receptor type 6 insulin receptor substrate 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 98 interactors: ABL1 ACTN1 ACTN4 BCR BLNK BTLA C6orf25 CAV1 CBL CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ESR1 FAS FCGR2B FCRL3 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRAP1 KLRB1 KLRC1 LAIR1 LCK LCP2 LIFR LILRB2 LILRB4 LYN MS4A2 MYH9 NOS1 PAG1 PECAM1 PIK3R1 PILRA PILRB PRKCA PRKCD PTK2B PTPN11 PTPRC ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF6 TREML1 TYK2 VAV1 ZAP70 17 interactors: CRK CRKL EGFR ERBB2 GRB2 IGF1R MTNR1A MTNR1B NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 SOCS6 SOCS7 YWHAG
Entrez ID 5777 8471
HPRD ID 01475 04620
Ensembl ID ENSG00000111679 ENSG00000133124
Uniprot IDs P29350 Q53XS4 O14654
PDB IDs 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a2  ag  cd45  chimera  chimeras  chimeric  coupling  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  phosphotyrosine  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction  unlike 
arg35  arhg5  cbl  cblb  del  digested  downscaled  doxycycline  dyn2  errfi  flp  hek293  hsp71  hsp7c  input  l747  optimisation  pc9  ptpra  purifications  quantities  retroviral  s752  sos1  sos2  tagged  tap  usb3b  wipf2 
Tagcloud (Difference) ?
a2  ag  cd45  chimera  chimeras  chimeric  coupling  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  phosphotyrosine  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction  unlike 
arg35  arhg5  cbl  cblb  del  digested  downscaled  doxycycline  dyn2  errfi  flp  hek293  hsp71  hsp7c  input  l747  optimisation  pc9  ptpra  purifications  quantities  retroviral  s752  sos1  sos2  tagged  tap  usb3b  wipf2 
Tagcloud (Intersection) ?