IGFBP3 and MMP2

  • Number of citations of the paper that reports this interaction (PMID 7523391)
  • 28
  • Data Source:
  • HPRD (in vitro)

IGFBP3

MMP2

Gene Name insulin-like growth factor binding protein 3 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 28 interactors: ADAM12 CAV1 CD44 COL1A1 CSNK2A1 CTSD CTSG CTSL F2 FN1 GPI GTF3C1 IGF1 IGF1R IGF2 IGFALS KLK3 KLKB1 KPNB1 LTBP1 MMP1 MMP2 MMP3 PAPPA2 PLG POLA2 RXRA TF 34 interactors: A2M ACAN BACE1 BCAN CCL7 CLDN1 COL18A1 COL1A1 COL6A3 COL7A1 CXCL12 DCN EPHB2 FGFR1 HAPLN1 HSP90AA1 IGFBP3 IL1B ITGAV KISS1 LCN2 LGALS3 MMP14 MMP17 MMP25 PZP SPOCK1 TGFB1 THBS1 THBS2 TIMP1 TIMP2 TIMP3 TIMP4
Entrez ID 3486 4313
HPRD ID 00899 00386
Ensembl ID ENSG00000146674 ENSG00000087245
Uniprot IDs B3KPF0 B3KWK7 P17936 P08253
PDB IDs 1CK7 1CXW 1EAK 1GEN 1GXD 1HOV 1J7M 1KS0 1QIB 1RTG 3AYU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bioavailability  bioavailable  breast  circulating  clinically  correlation  ectopic  epithelium  expansion  igf1  igfr  inducer  majority  mammary  mitosis  modulated  oestradiol  oestrogen  possibly  postulated  shown  specimens  status  stimulate  stimulating  synergize  upregulate  xenografts 
5microm  actin  anxa2  beside  depend  depends  evoked  fibroblasts  fro  h2o2  likewise  metalloproteinase  mitogenic  mmps  nsmase2  p38mapk  peroxide  pretreated  remodeling  reorganization  ro28  sb203580  shape  smc  sphingolipid  sphingomyelinase  src  triggered  unable 
Tagcloud (Difference) ?
bioavailability  bioavailable  breast  circulating  clinically  correlation  ectopic  epithelium  expansion  igf1  igfr  inducer  majority  mammary  mitosis  modulated  oestradiol  oestrogen  possibly  postulated  shown  specimens  status  stimulate  stimulating  synergize  upregulate  xenografts 
5microm  actin  anxa2  beside  depend  depends  evoked  fibroblasts  fro  h2o2  likewise  metalloproteinase  mitogenic  mmps  nsmase2  p38mapk  peroxide  pretreated  remodeling  reorganization  ro28  sb203580  shape  smc  sphingolipid  sphingomyelinase  src  triggered  unable 
Tagcloud (Intersection) ?