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FAM131C and GRN
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
FAM131C
GRN
Gene Name
family with sequence similarity 131, member C
granulin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Mitochondrion
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Cytokine Activity
Protein Binding
Growth Factor Activity
Poly(A) RNA Binding
Biological Process
Blastocyst Hatching
Signal Transduction
Embryo Implantation
Positive Regulation Of Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Cognitive performance (
19734545
)
Intracranial volume (
22504418
)
Protein-Protein Interactions
10 interactors:
APP
DNAJA3
EWSR1
GRN
HPCAL4
LMO3
MAD1L1
NDN
SFI1
VSNL1
37 interactors:
ARFGAP1
ATN1
ATXN7
CACNA1A
CCDC33
CCNG1
CCNT1
CDK9
CRKL
CRY1
DLK1
DLX2
ELANE
FAM131C
FANCL
FRAT1
GFI1B
GLRX3
HK3
HOXA1
HSPG2
KRT18
KRTAP10-7
KRTAP26-1
NLK
OTX1
PIK3R2
POT1
PRKAB2
RAC1
SGTA
SLPI
SMAD9
TAT
TGM2
TOP3B
YY1
Entrez ID
348487
2896
HPRD ID
08779
00733
Ensembl ID
ENSG00000185519
ENSG00000030582
Uniprot IDs
Q96AQ9
P28799
PDB IDs
1G26
2JYE
2JYT
2JYU
2JYV
Enriched GO Terms of Interacting Partners
?
Neuron Recognition
Neuromuscular Junction Development
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Regulation Of Metaphase Plate Congression
Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Regulation Of Protein Processing
Negative Regulation Of Hydrolase Activity
Developmental Cell Growth
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Cell Recognition
Collateral Sprouting In Absence Of Injury
Developmental Growth Involved In Morphogenesis
Positive Regulation Of Peptidase Activity
Cell Growth
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Proteolysis
Synapse Organization
Regulation Of Phosphorus Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Axon Choice Point Recognition
Activation-induced Cell Death Of T Cells
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Catalytic Activity
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Neuron Remodeling
Blastocyst Hatching
Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Skeletal Muscle Acetylcholine-gated Channel Clustering
Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Endopeptidase Activity
Mitochondrial DNA Replication
Negative Regulation Of Peptidase Activity
Developmental Growth
Response To Organic Substance
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Central Nervous System Development
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Cellular Process
Regulation Of Metabolic Process
Brain Development
Regulation Of Kinase Activity
Head Development
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Positive Regulation Of Cellular Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Transcription, DNA-templated
Regulation Of Cellular Protein Metabolic Process
Pattern Specification Process
RNA Biosynthetic Process
Regulation Of Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
Organ Morphogenesis
Anatomical Structure Morphogenesis
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Embryonic Organ Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Embryonic Skeletal System Development
Response To Light Stimulus
Hindbrain Development
Regulation Of Protein Metabolic Process
Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Phosphorus Metabolic Process
Pons Development
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Regulation Of Signal Transduction
Cellular Aromatic Compound Metabolic Process
Central Nervous System Neuron Differentiation
Anatomical Structure Development
Positive Regulation Of Transcription, DNA-templated
Tagcloud
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Difference)
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Intersection)
?