APEX1 and HIF1A

  • Number of citations of the paper that reports this interaction (PMID 10594042)
  • 72
  • Data Source:
  • HPRD (in vitro)

APEX1

HIF1A

Gene Name APEX nuclease (multifunctional DNA repair enzyme) 1 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: ANP32A ANP32C APP CSNK2A1 DCTN1 EP300 FEN1 GZMA GZMK HDAC1 HIF1A HMGA1 HMGA2 HMGB2 HNRNPL HOXC13 HSPA1A MDM2 MUTYH NME1 NUDT3 NXF2 PCNA POLB POLR3D SET SRPK1 SRPK2 TCF21 TERF1 TERF2 TERF2IP TP53 TXN UBE2I XRCC1 XRCC5 XRCC6 67 interactors: APEX1 AR ARNT ARNT2 ARNTL ATM CDC34 CDKN2A CITED2 COPS5 CREBBP CSNK2A1 CTNNB1 DAP3 EGLN1 EGLN2 EGLN3 EP300 FHL2 GNB2L1 HDAC1 HDAC2 HDAC5 HIF1AN HIF3A HSP90AA1 HSP90AB1 JUN MAFG MAFK MAPK1 MAPK3 MAX MCM7 MDM2 MTA1 NAA10 NAA11 NCOA1 NCOA2 NDN NR4A1 OS9 PER1 PGK1 PKM PLD1 PSMA7 RB1 RUNX2 RWDD3 SAT1 SEPT9 SP1 SSX4 STAT3 STUB1 SUMO1 SUMO2 TP53 TRAF6 TSGA10 UBE2D1 USP19 USP20 VHL VHLL
Entrez ID 328 3091
HPRD ID 00136 04517
Ensembl ID ENSG00000100823 ENSG00000100644
Uniprot IDs P27695 Q5TZP7 A8MYV6 D0VY79 Q16665
PDB IDs 1BIX 1CQG 1CQH 1DE8 1DE9 1DEW 1E9N 1HD7 2ISI 2O3H 3U8U 4IEM 1D7G 1H2K 1H2L 1H2M 1L3E 1L8C 1LM8 1LQB 2ILM 3HQR 3HQU 4AJY 4H6J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
apurinic  apyriminidinic  asp  carcinogenesis  carrying  contribution  correlates  drinking  endometriosis  endonuclease  evaluating  genotype  genotypes  genotyping  gg  glu  instability  joint  lifestyles  menarche  polymorphic  prediction  q  restriction  rflp  rs1130409  taiwan  tg  tt 
actual  ahr  analytic  atf4  becomes  datasets  hepato  lists  mechanistically  mining  modulation  nephro  nrf2  omic  ppar  precision  promise  publicly  seq  signatures  tcx  tf  tfs  thorough  toxicological  toxins  tracked  transcriptomics  xbp1 
Tagcloud (Difference) ?
apurinic  apyriminidinic  asp  carcinogenesis  carrying  contribution  correlates  drinking  endometriosis  endonuclease  evaluating  genotype  genotypes  genotyping  gg  glu  instability  joint  lifestyles  menarche  polymorphic  prediction  q  restriction  rflp  rs1130409  taiwan  tg  tt 
actual  ahr  analytic  atf4  becomes  datasets  hepato  lists  mechanistically  mining  modulation  nephro  nrf2  omic  ppar  precision  promise  publicly  seq  signatures  tcx  tf  tfs  thorough  toxicological  toxins  tracked  transcriptomics  xbp1 
Tagcloud (Intersection) ?