HIF1A and EGLN3

  • Number of citations of the paper that reports this interaction (PMID 15721254)
  • 40
  • Data Source:
  • BioGRID (two hybrid, fluorescent resonance energy transfer)
  • HPRD (in vivo, in vitro)

HIF1A

EGLN3

Gene Name hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) egl-9 family hypoxia-inducible factor 3
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 67 interactors: APEX1 AR ARNT ARNT2 ARNTL ATM CDC34 CDKN2A CITED2 COPS5 CREBBP CSNK2A1 CTNNB1 DAP3 EGLN1 EGLN2 EGLN3 EP300 FHL2 GNB2L1 HDAC1 HDAC2 HDAC5 HIF1AN HIF3A HSP90AA1 HSP90AB1 JUN MAFG MAFK MAPK1 MAPK3 MAX MCM7 MDM2 MTA1 NAA10 NAA11 NCOA1 NCOA2 NDN NR4A1 OS9 PER1 PGK1 PKM PLD1 PSMA7 RB1 RUNX2 RWDD3 SAT1 SEPT9 SP1 SSX4 STAT3 STUB1 SUMO1 SUMO2 TP53 TRAF6 TSGA10 UBE2D1 USP19 USP20 VHL VHLL 22 interactors: ABI2 ADRB2 ATF4 EFHC2 EPAS1 FOXJ2 HIF1A HIF3A IKBKG MAPK1 MAPK6 MAPK7 NCAPH2 OS9 PKM PRPF19 REL SERTAD1 SIAH2 SQSTM1 TTC23L WDR83
Entrez ID 3091 112399
HPRD ID 04517 06972
Ensembl ID ENSG00000100644 ENSG00000129521
Uniprot IDs A8MYV6 D0VY79 Q16665 Q9H6Z9
PDB IDs 1D7G 1H2K 1H2L 1H2M 1L3E 1L8C 1LM8 1LQB 2ILM 3HQR 3HQU 4AJY 4H6J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actual  ahr  analytic  atf4  becomes  datasets  hepato  lists  mechanistically  mining  modulation  nephro  nrf2  omic  ppar  precision  promise  publicly  seq  signatures  tcx  tf  tfs  thorough  toxicological  toxins  tracked  transcriptomics  xbp1 
altering  avenue  cyclin  d1  deubiquitinase  egln1  egln2  foxo  foxo3a  hif  hydroxylases  hydroxylate  hydroxylation  insights  leads  pharmacologically  prevents  prolyl  promotes  promoting  proteasomal  regulate  repress  stability  suppresses  thereby  turn  usp9x 
Tagcloud (Difference) ?
actual  ahr  analytic  atf4  becomes  datasets  hepato  lists  mechanistically  mining  modulation  nephro  nrf2  omic  ppar  precision  promise  publicly  seq  signatures  tcx  tf  tfs  thorough  toxicological  toxins  tracked  transcriptomics  xbp1 
altering  avenue  cyclin  d1  deubiquitinase  egln1  egln2  foxo  foxo3a  hif  hydroxylases  hydroxylate  hydroxylation  insights  leads  pharmacologically  prevents  prolyl  promotes  promoting  proteasomal  regulate  repress  stability  suppresses  thereby  turn  usp9x 
Tagcloud (Intersection) ?