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APBB1 and WAS
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
APBB1
WAS
Gene Name
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Wiskott-Aldrich syndrome
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Nuclear Speck
Lamellipodium
Growth Cone
Synapse
Cytosol
Cell-cell Junction
Vesicle Membrane
Actin Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Beta-amyloid Binding
Chromatin Binding
Protein Binding
Transcription Factor Binding
Histone Binding
Proline-rich Region Binding
Actin Binding
Small GTPase Regulator Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Identical Protein Binding
Phospholipase Binding
Biological Process
Neuron Migration
Double-strand Break Repair
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle Arrest
Signal Transduction
Axonogenesis
Axon Guidance
Visual Learning
Extracellular Matrix Organization
Negative Regulation Of Cell Growth
Positive Regulation Of Apoptotic Process
Histone H4 Acetylation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of DNA Repair
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Protein Complex Assembly
Defense Response
Immune Response
Blood Coagulation
Actin Polymerization Or Depolymerization
Epidermis Development
Endosomal Transport
Actin Filament Polymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
T Cell Activation
Innate Immune Response
Regulation Of Catalytic Activity
T Cell Receptor Signaling Pathway
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
TCR signaling
Generation of second messenger molecules
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
66 interactors:
ABI1
ABL1
ANXA1
APLP1
APLP2
APP
ATXN1
ATXN1L
CCDC97
CHERP
CLSTN1
CPSF6
CPSF7
CYFIP1
CYFIP2
DDX17
DDX3X
DDX46
DHX15
DHX9
DIAPH1
DIAPH2
EGFR
ENAH
ERBB2
EVL
FASLG
HNRNPH1
HNRNPK
HTATSF1
KAT5
KHDRBS1
KHSRP
LRP1
LRP2
NONO
PABPC1
PQBP1
PRNP
PTBP1
RBM17
RPL4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
TFCP2
THRAP3
TSHZ1
TSHZ2
TSHZ3
U2AF2
VASP
WAS
WASF2
WASL
WBP11
WIPF1
WIPF2
YBX1
YLPM1
53 interactors:
ABI3
ACTC1
APBB1
APPBP2
ARHGAP1
ARHGEF7
ARPC1B
ARPC2
ARPC3
BAIAP2L1
BTK
C5AR1
CDC42
CIB1
CRKL
CSNK2A1
CSNK2A2
DLG1
ENAH
EVL
FCHSD2
FGR
FYB
FYN
GAS7
GRB2
HCK
HCLS1
ITK
ITSN2
LCK
LCP2
NCK1
NCK2
NCKIPSD
PIK3R1
PLCG1
PRPF40A
PSTPIP1
PTPN12
RAC1
RGS14
RHOJ
SORBS2
SRC
TCERG1
TEC
TNK2
TRIP10
VASP
WBP4
WIPF1
WIPF2
Entrez ID
322
7454
HPRD ID
04087
02314
Ensembl ID
ENSG00000166313
ENSG00000015285
Uniprot IDs
O00213
P42768
PDB IDs
2E45
2HO2
2IDH
2OEI
3D8D
3D8E
3D8F
3DXC
3DXD
3DXE
1CEE
1EJ5
1T84
2A3Z
2K42
2OT0
Enriched GO Terms of Interacting Partners
?
RNA Processing
MRNA Processing
MRNA Metabolic Process
RNA Splicing
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Actin Polymerization Or Depolymerization
RNA Biosynthetic Process
MRNA 3'-splice Site Recognition
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Transcription, DNA-templated
Fc Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Immune Response-regulating Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Actin Filament Organization
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Component Assembly
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Phagocytosis
MRNA 3'-end Processing
Cellular Process
Regulation Of Metabolic Process
Endocytosis
Innate Immune Response
Multicellular Organismal Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of RNA Splicing
RNA 3'-end Processing
Actin Cytoskeleton Organization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Developmental Process
Actin Filament-based Process
MRNA Stabilization
Axon Guidance
Positive Regulation Of Actin Nucleation
MRNA Polyadenylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Immune System Process
Locomotion
Axon Guidance
Regulation Of Immune Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune System Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Filament Organization
Innate Immune Response
Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Axonogenesis
Neuron Projection Morphogenesis
Immune Response
Positive Regulation Of Protein Polymerization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Development
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Neuron Differentiation
Phagocytosis
Positive Regulation Of Protein Complex Assembly
Cell Morphogenesis Involved In Differentiation
Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament Polymerization
Cell Surface Receptor Signaling Pathway
Endocytosis
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Length
Neuron Projection Development
Regulation Of Cellular Component Organization
Antigen Receptor-mediated Signaling Pathway
Cell Projection Morphogenesis
Cell Part Morphogenesis
Response To External Stimulus
Signal Transduction
T Cell Receptor Signaling Pathway
Signaling
Tagcloud
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Difference)
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Intersection)
?