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APBB1 and WIPF1
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
APBB1
WIPF1
Gene Name
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
WAS/WASL interacting protein family, member 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Nuclear Speck
Lamellipodium
Growth Cone
Synapse
Ruffle
Cytosol
Actin Filament
Actin Cytoskeleton
Cytoplasmic Membrane-bounded Vesicle
Molecular Function
Beta-amyloid Binding
Chromatin Binding
Protein Binding
Transcription Factor Binding
Histone Binding
Proline-rich Region Binding
Actin Binding
Protein Binding
Profilin Binding
Biological Process
Neuron Migration
Double-strand Break Repair
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle Arrest
Signal Transduction
Axonogenesis
Axon Guidance
Visual Learning
Extracellular Matrix Organization
Negative Regulation Of Cell Growth
Positive Regulation Of Apoptotic Process
Histone H4 Acetylation
Negative Regulation Of Neuron Differentiation
Positive Regulation Of DNA Repair
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Protein Complex Assembly
Actin Polymerization Or Depolymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Response To Other Organism
Pathways
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
66 interactors:
ABI1
ABL1
ANXA1
APLP1
APLP2
APP
ATXN1
ATXN1L
CCDC97
CHERP
CLSTN1
CPSF6
CPSF7
CYFIP1
CYFIP2
DDX17
DDX3X
DDX46
DHX15
DHX9
DIAPH1
DIAPH2
EGFR
ENAH
ERBB2
EVL
FASLG
HNRNPH1
HNRNPK
HTATSF1
KAT5
KHDRBS1
KHSRP
LRP1
LRP2
NONO
PABPC1
PQBP1
PRNP
PTBP1
RBM17
RPL4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
TFCP2
THRAP3
TSHZ1
TSHZ2
TSHZ3
U2AF2
VASP
WAS
WASF2
WASL
WBP11
WIPF1
WIPF2
YBX1
YLPM1
22 interactors:
ABI2
ACTC1
ACTG1
ALAS1
APBB1
CDC42
CRKL
CTTN
FASTK
GRB2
HCK
HOMER3
ITSN2
NCK1
PRKCQ
PRPF40A
SEC24C
WAS
WASL
WBP4
WWP2
ZAP70
Entrez ID
322
7456
HPRD ID
04087
03835
Ensembl ID
ENSG00000166313
ENSG00000115935
Uniprot IDs
O00213
O43516
Q2YDC4
PDB IDs
2E45
2HO2
2IDH
2OEI
3D8D
3D8E
3D8F
3DXC
3DXD
3DXE
2A41
Enriched GO Terms of Interacting Partners
?
RNA Processing
MRNA Processing
MRNA Metabolic Process
RNA Splicing
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Actin Polymerization Or Depolymerization
RNA Biosynthetic Process
MRNA 3'-splice Site Recognition
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Transcription, DNA-templated
Fc Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Immune Response-regulating Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Actin Filament Organization
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Component Assembly
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Phagocytosis
MRNA 3'-end Processing
Cellular Process
Regulation Of Metabolic Process
Endocytosis
Innate Immune Response
Multicellular Organismal Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of RNA Splicing
RNA 3'-end Processing
Actin Cytoskeleton Organization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Developmental Process
Actin Filament-based Process
MRNA Stabilization
Axon Guidance
Positive Regulation Of Actin Nucleation
MRNA Polyadenylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Locomotion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-regulating Signaling Pathway
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Immune Response
Phagocytosis
Endocytosis
Actin Filament Organization
Regulation Of Cytoskeleton Organization
Innate Immune Response
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Neuron Projection Development
Regulation Of Actin Cytoskeleton Organization
Cell Migration
Actin Cytoskeleton Organization
Positive Regulation Of Actin Nucleation
Regulation Of Immune Response
Axon Guidance
Cell Motility
Positive Regulation Of Immune System Process
Positive Regulation Of Organelle Organization
Actin Filament-based Process
Regulation Of Actin Filament-based Process
Neuron Projection Morphogenesis
Neuron Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Vesicle-mediated Transport
Cytoskeleton Organization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cellular Component Organization
Neuron Differentiation
Axonogenesis
Cell Projection Organization
Cell Projection Morphogenesis
Axon Development
Cell Part Morphogenesis
Actin Polymerization Or Depolymerization
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Regulation Of Organelle Organization
Immune System Process
Immune Response
Tagcloud
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Difference)
?
a4
additive
aging
amyloid
apba3
aplp1
apolipoprotein
c57bl
clues
dysregulation
elusive
fe65
hippocampal
hypertension
hypertensive
impairments
m1
manifestation
maze
mint3
mo
muscarinic
object
precursor
predisposes
secretases
signature
tauopathy
wk
Tagcloud (Intersection)
?