EGLN3 and FOXJ2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EGLN3	FOXJ2
Gene Name		egl-9 family hypoxia-inducible factor 3	forkhead box J2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleolus
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors L-ascorbic Acid Binding Peptidyl-proline 4-dioxygenase Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding
	Biological Process	Response To Hypoxia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Hydroxylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Regulation Of Cell Proliferation Regulation Of Neuron Apoptotic Process Oxidation-reduction Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ABI2 ADRB2 ATF4 EFHC2 EPAS1 FOXJ2 HIF1A HIF3A IKBKG MAPK1 MAPK6 MAPK7 NCAPH2 OS9 PKM PRPF19 REL SERTAD1 SIAH2 SQSTM1 TTC23L WDR83	2 interactors: APP EGLN3
Entrez ID		112399	55810
HPRD ID		06972	17014
Ensembl ID		ENSG00000129521	ENSG00000065970
Uniprot IDs		Q9H6Z9	Q9P0K8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stress Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Metabolic Process Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Signal Transduction Negative Regulation Of Cell Death Regulation Of Cellular Response To Oxidative Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway RNA Metabolic Process Signaling Cellular Response To Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Communication Regulation Of Gene Expression TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Neuron Death MyD88-independent Toll-like Receptor Signaling Pathway Negative Regulation Of Neuron Death Toll-like Receptor 3 Signaling Pathway Gene Expression Regulation Of Protein Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Transcription, DNA-templated MAPK Cascade Positive Regulation Of Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Transcription, DNA-templated	Positive Regulation Of Peptidase Activity Synaptic Growth At Neuromuscular Junction Positive Regulation Of Proteolysis Collateral Sprouting In Absence Of Injury Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Proteolysis Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Cellular Copper Ion Homeostasis Apoptotic Process 4-hydroxyproline Metabolic Process Copper Ion Homeostasis Suckling Behavior Programmed Cell Death Positive Regulation Of Hydrolase Activity Cell Death Death Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Abiotic Stimulus Peptidyl-proline Hydroxylation Positive Regulation Of Cellular Protein Metabolic Process Protein Hydroxylation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Protein Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Catalytic Activity Axon Cargo Transport Mating Neuromuscular Junction Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Tyrosine Kinase Activity
Tagcloud ?		altering avenue cyclin d1 deubiquitinase egln1 egln2 foxo foxo3a hif hydroxylases hydroxylate hydroxylation insights leads pharmacologically prevents prolyl promotes promoting proteasomal regulate repress stability suppresses thereby turn usp9x	7b alteration alters bh3 biosynthesis cholesterol chop clues downregulation ebp emerged h460 hmgcr hmgcs1 idi1 inverse let lna mirna mirnas mirnome nac nci played respective scavenger silencing stat6 utr
Tagcloud (Difference) ?		altering avenue cyclin d1 deubiquitinase egln1 egln2 foxo foxo3a hif hydroxylases hydroxylate hydroxylation insights leads pharmacologically prevents prolyl promotes promoting proteasomal regulate repress stability suppresses thereby turn usp9x	7b alteration alters bh3 biosynthesis cholesterol chop clues downregulation ebp emerged h460 hmgcr hmgcs1 idi1 inverse let lna mirna mirnas mirnome nac nci played respective scavenger silencing stat6 utr
Tagcloud (Intersection) ?