EGLN3 and SERTAD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EGLN3	SERTAD1
Gene Name		egl-9 family hypoxia-inducible factor 3	SERTA domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors L-ascorbic Acid Binding Peptidyl-proline 4-dioxygenase Activity	Protein Binding
	Biological Process	Response To Hypoxia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Hydroxylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Regulation Of Cell Proliferation Regulation Of Neuron Apoptotic Process Oxidation-reduction Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated
Pathways		Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ABI2 ADRB2 ATF4 EFHC2 EPAS1 FOXJ2 HIF1A HIF3A IKBKG MAPK1 MAPK6 MAPK7 NCAPH2 OS9 PKM PRPF19 REL SERTAD1 SIAH2 SQSTM1 TTC23L WDR83	36 interactors: ASB8 ATXN7L3 CCND2 CDK4 CDKN2A CHURC1 CIB3 COPB1 CREBBP DENND4A EGLN3 EP300 FAH HIVEP1 HSPB1 KAT2B KLHL42 MVP P4HA3 PATE1 POT1 PRDM4 RBX1 RCHY1 ROPN1 SETD7 SFI1 SMAD3 SPEN STAT5B SUPT7L TCEB1 TGM2 TLR4 TRIM28 ZNF410
Entrez ID		112399	29950
HPRD ID		06972	15326
Ensembl ID		ENSG00000129521
Uniprot IDs		Q9H6Z9	Q53GC0 Q9UHV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stress Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Metabolic Process Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Signal Transduction Negative Regulation Of Cell Death Regulation Of Cellular Response To Oxidative Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway RNA Metabolic Process Signaling Cellular Response To Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Communication Regulation Of Gene Expression TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Neuron Death MyD88-independent Toll-like Receptor Signaling Pathway Negative Regulation Of Neuron Death Toll-like Receptor 3 Signaling Pathway Gene Expression Regulation Of Protein Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Transcription, DNA-templated MAPK Cascade Positive Regulation Of Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Response To Hypoxia Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Cellular Protein Modification Process Macromolecule Biosynthetic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Oxygen Levels N-terminal Protein Amino Acid Acetylation Viral Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Notch Signaling Pathway Negative Regulation Of Cellular Metabolic Process Cellular Protein Metabolic Process Peptidyl-amino Acid Modification Protein Metabolic Process Chromatin Organization Chromosome Organization Positive Regulation Of Interleukin-1 Production N-terminal Protein Amino Acid Modification Positive Regulation Of Cytokine Production Response To Abiotic Stimulus
Tagcloud ?		altering avenue cyclin d1 deubiquitinase egln1 egln2 foxo foxo3a hif hydroxylases hydroxylate hydroxylation insights leads pharmacologically prevents prolyl promotes promoting proteasomal regulate repress stability suppresses thereby turn usp9x
Tagcloud (Difference) ?		altering avenue cyclin d1 deubiquitinase egln1 egln2 foxo foxo3a hif hydroxylases hydroxylate hydroxylation insights leads pharmacologically prevents prolyl promotes promoting proteasomal regulate repress stability suppresses thereby turn usp9x
Tagcloud (Intersection) ?