H2AFX and PRKDC

  • Number of citations of the paper that reports this interaction (PMID 22184063)
  • 5
  • Data Source:
  • BioGRID (enzymatic study)

H2AFX

PRKDC

Gene Name H2A histone family, member X protein kinase, DNA-activated, catalytic polypeptide
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 45 interactors: A2M ACTB ALG9 ATM ATR BARD1 BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 KAT5 MASP1 MCPH1 MDC1 MRE11A NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PPP2R4 PRKDC QARS RNF168 RNF8 RPS6KA3 SMARCA4 SSRP1 SUPT16H SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TSSK6 WRN XRCC6 83 interactors: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CHEK1 CHEK2 CHUK CIB1 CTDP1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 ERG GSK3A GSK3B GZMB H2AFX HDAC3 HIST1H1A HIST1H1C HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11A NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R2 PPP6R3 PRKCD PTS RAD17 RBBP8 RNF144A RPA1 RPA2 SGOL1 SP1 SRF THRA THRB TP53 TREX1 UBC USF1 VPRBP WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ
Entrez ID 3014 5591
HPRD ID 03465 02941
Ensembl ID ENSG00000188486 ENSG00000253729
Uniprot IDs P16104 P78527
PDB IDs 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1ada  1p24  antiretroviral  atazanavir  atv  boosted  capacities  carriage  coating  depots  fa  folic  il2rg  loads  mirrored  nanoart  nanocrystals  nanoformulated  p407  parafollicular  paralleled  permit  pharmacodynamic  poloxamer  reconstituted  ritonavir  szj  tm1wjl  untargeted 
Tagcloud (Difference) ?
1ada  1p24  antiretroviral  atazanavir  atv  boosted  capacities  carriage  coating  depots  fa  folic  il2rg  loads  mirrored  nanoart  nanocrystals  nanoformulated  p407  parafollicular  paralleled  permit  pharmacodynamic  poloxamer  reconstituted  ritonavir  szj  tm1wjl  untargeted 
Tagcloud (Intersection) ?