TNPO2 and KLHL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TNPO2	KLHL2
Gene Name		transportin 2	kelch-like family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding	Actin Binding Protein Binding
	Biological Process	Intracellular Protein Transport	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: A1CF APIP C1orf94 CAMK2D CRYAB ELAVL1 EXOC5 KLHL2 NME1 NUP98 NXF1 PIK3CD PNMA5 RAN TCL1B TERF1	15 interactors: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114
Entrez ID		30000	11275
HPRD ID		04301	09311
Ensembl ID		ENSG00000105576	ENSG00000109466
Uniprot IDs		O14787 Q05D48 Q4LE60	O95198
PDB IDs			2XN4
Enriched GO Terms of Interacting Partners?		RNA Localization Nucleocytoplasmic Transport Nuclear Transport Regulation Of Apoptotic Process Protein Import Into Nucleus, Docking Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cytidine To Uridine Editing L-methionine Biosynthetic Process From S-adenosylmethionine Intracellular Transport Regulation Of Cell Death Cellular Localization Ribosomal Small Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Natural Killer Cell Chemotaxis B Cell Chemotaxis Mast Cell Differentiation Telomeric Loop Formation Age-dependent Telomere Shortening Protein Oligomerization MRNA Transport Nuclear Export Protein Import Into Nucleus Positive Regulation Of Binding Neutrophil Extravasation Telomere Maintenance Via Telomere Shortening Mast Cell Chemotaxis Regulation Of Generation Of L-type Calcium Current Protein Complex Assembly Nuclear Import DNA Metabolic Process RNA Transport Positive Regulation Of Rac Protein Signal Transduction Respiratory Burst Involved In Defense Response S-adenosylmethionine Cycle Regulation Of Histone Deacetylase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Sodium Ion Transmembrane Transporter Activity MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Viral Process Protein Import Base Conversion Or Substitution Editing Nuclear Pore Complex Assembly Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Establishment Of Localization In Cell Protein Localization To Nucleus Ribosomal Large Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential	Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Pancreatic Juice Secretion Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Segregation Negative Regulation Of Transferase Activity Regulation Of Mitotic Nuclear Division COPII Vesicle Coating Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process COPII-coated Vesicle Budding Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Regulation Of Chromosome Organization Spindle Assembly Checkpoint Protein K48-linked Ubiquitination Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Protein Ubiquitination Mitotic Spindle Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitotic Nuclear Division Protein Monoubiquitination Localization Within Membrane Negative Regulation Of Chromosome Segregation Vesicle Targeting Regulation Of Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Cell Division Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Proteolysis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Catalytic Activity Cellular Protein Modification Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?