TNPO2 and FUCA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNPO2	FUCA2
Description		transportin 2	alpha-L-fucosidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Alpha-L-fucosidase Activity Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Negative Regulation Of Muscle Cell Differentiation	Carbohydrate Metabolic Process Fucose Metabolic Process Response To Bacterium Glycoside Catabolic Process Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)	Multiple sclerosis ( 31604244)
Interacting Genes		54 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CEBPA CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RBM45 REDIC1 RIPK4 RNF10 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C	19 interacting genes: GPR37 GPRC5B GUCD1 HOXA1 KRTAP10-1 KRTAP4-12 KRTAP5-2 KRTAP5-3 LCE1A LCE1B LCE1E LCE4A MEOX2 NUFIP2 OGT PIN1 TNPO2 VWC2 WNT11
Entrez ID		30000	2519
HPRD ID		04301	00649
Ensembl ID		ENSG00000105576	ENSG00000001036
Uniprot IDs		O14787 Q05D48	Q9BTY2
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Protein Homodimerization Activity	Keratinization Epidermis Development Intermediate Filament Tissue Development Somite Development
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