TNPO2 and NUP98

Number of citations of the paper that reports this interaction (PMID 10875935)
20

Data Source:
BioGRID (pull down, pull down)

		TNPO2	NUP98
Gene Name		transportin 2	nucleoporin 98kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding	Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Peptide Binding
	Biological Process	Intracellular Protein Transport	Protein Import Into Nucleus, Docking Mitotic Cell Cycle Carbohydrate Metabolic Process DNA Replication Nucleocytoplasmic Transport Nuclear Pore Organization Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: A1CF APIP C1orf94 CAMK2D CRYAB ELAVL1 EXOC5 KLHL2 NME1 NUP98 NXF1 PIK3CD PNMA5 RAN TCL1B TERF1	18 interactors: APC CREBBP CSNK2A1 EP300 HDAC1 IPO5 KPNB1 NFX1 NUP133 NUP62 NUP88 NXF1 RAE1 RCC1 SEC13 TNPO1 TNPO2 TPR
Entrez ID		30000	4928
HPRD ID		04301	03012
Ensembl ID		ENSG00000105576	ENSG00000110713
Uniprot IDs		O14787 Q05D48 Q4LE60	P52948
PDB IDs			1KO6 2Q5X 2Q5Y 3MMY
Enriched GO Terms of Interacting Partners?		RNA Localization Nucleocytoplasmic Transport Nuclear Transport Regulation Of Apoptotic Process Protein Import Into Nucleus, Docking Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cytidine To Uridine Editing L-methionine Biosynthetic Process From S-adenosylmethionine Intracellular Transport Regulation Of Cell Death Cellular Localization Ribosomal Small Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Natural Killer Cell Chemotaxis B Cell Chemotaxis Mast Cell Differentiation Telomeric Loop Formation Age-dependent Telomere Shortening Protein Oligomerization MRNA Transport Nuclear Export Protein Import Into Nucleus Positive Regulation Of Binding Neutrophil Extravasation Telomere Maintenance Via Telomere Shortening Mast Cell Chemotaxis Regulation Of Generation Of L-type Calcium Current Protein Complex Assembly Nuclear Import DNA Metabolic Process RNA Transport Positive Regulation Of Rac Protein Signal Transduction Respiratory Burst Involved In Defense Response S-adenosylmethionine Cycle Regulation Of Histone Deacetylase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Sodium Ion Transmembrane Transporter Activity MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Viral Process Protein Import Base Conversion Or Substitution Editing Nuclear Pore Complex Assembly Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Establishment Of Localization In Cell Protein Localization To Nucleus Ribosomal Large Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential	Viral Process Mitotic Cell Cycle MRNA Transport RNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Localization Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cell Cycle Mitotic Cell Cycle Process Cytoplasmic Transport Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Life Cycle Viral Transcription Regulation Of Glucose Transport Cell Cycle Process Nucleus Organization Intracellular Transport Carbohydrate Transport MRNA Export From Nucleus RNA Export From Nucleus Protein Transport Organelle Organization Establishment Of Protein Localization Establishment Of Localization In Cell Pathogenesis Cytokine-mediated Signaling Pathway Gene Expression Protein Import Into Nucleus Nuclear Import N-terminal Peptidyl-lysine Acetylation Nuclear Export Regulation Of Mitotic Nuclear Division RNA Biosynthetic Process Cellular Localization Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Cellular Response To Cytokine Stimulus Protein Localization Mitotic Spindle Checkpoint Protein Import Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Protein Localization To Nucleus Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition
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