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TNPO2 and APIP
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TNPO2
APIP
Gene Name
transportin 2
APAF1 interacting protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytoplasm
Molecular Function
Protein Binding
Nuclear Localization Sequence Binding
Ran GTPase Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Methylthioribulose 1-phosphate Dehydratase Activity
Biological Process
Intracellular Protein Transport
Sulfur Amino Acid Metabolic Process
Polyamine Metabolic Process
Apoptotic Process
L-methionine Biosynthetic Process From S-adenosylmethionine
L-methionine Biosynthetic Process From Methylthioadenosine
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Apoptotic Process
Small Molecule Metabolic Process
Regulation Of ERK1 And ERK2 Cascade
Pathways
Metabolism of polyamines
Sulfur amino acid metabolism
Methionine salvage pathway
Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Cystic fibrosis severity (
21602797
)
Protein-Protein Interactions
16 interactors:
A1CF
APIP
C1orf94
CAMK2D
CRYAB
ELAVL1
EXOC5
KLHL2
NME1
NUP98
NXF1
PIK3CD
PNMA5
RAN
TCL1B
TERF1
17 interactors:
APAF1
C6orf165
IMPDH2
LNX1
NIF3L1
NUDT18
PDZD4
PPP1CC
PSMA1
SDCBP
SKP1
TNPO2
TSC22D4
VIM
VPS25
WDYHV1
ZBTB25
Entrez ID
30000
51074
HPRD ID
04301
14725
Ensembl ID
ENSG00000105576
ENSG00000149089
Uniprot IDs
O14787
Q05D48
Q4LE60
J3KN82
Q96GX9
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Localization
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Apoptotic Process
Protein Import Into Nucleus, Docking
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Cytidine To Uridine Editing
L-methionine Biosynthetic Process From S-adenosylmethionine
Intracellular Transport
Regulation Of Cell Death
Cellular Localization
Ribosomal Small Subunit Export From Nucleus
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Cardiac Muscle Cell Contraction
Natural Killer Cell Chemotaxis
B Cell Chemotaxis
Mast Cell Differentiation
Telomeric Loop Formation
Age-dependent Telomere Shortening
Protein Oligomerization
MRNA Transport
Nuclear Export
Protein Import Into Nucleus
Positive Regulation Of Binding
Neutrophil Extravasation
Telomere Maintenance Via Telomere Shortening
Mast Cell Chemotaxis
Regulation Of Generation Of L-type Calcium Current
Protein Complex Assembly
Nuclear Import
DNA Metabolic Process
RNA Transport
Positive Regulation Of Rac Protein Signal Transduction
Respiratory Burst Involved In Defense Response
S-adenosylmethionine Cycle
Regulation Of Histone Deacetylase Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Viral Process
Protein Import
Base Conversion Or Substitution Editing
Nuclear Pore Complex Assembly
Negative Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Relaxation Of Cardiac Muscle
Establishment Of Localization In Cell
Protein Localization To Nucleus
Ribosomal Large Subunit Export From Nucleus
Regulation Of Cardiac Muscle Cell Action Potential
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Catabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
GDP Catabolic Process
Response To G1 DNA Damage Checkpoint Signaling
DGDP Catabolic Process
DADP Catabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Macromolecule Catabolic Process
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Dihydrobiopterin Metabolic Process
Positive Regulation Of Extracellular Vesicular Exosome Assembly
GMP Biosynthetic Process
Positive Regulation Of Protein Ubiquitination
Regulation Of Extracellular Vesicular Exosome Assembly
Purine Ribonucleoside Diphosphate Catabolic Process
Endosome Transport Via Multivesicular Body Sorting Pathway
Nucleobase-containing Small Molecule Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Late Endosome To Vacuole Transport
Viral Process
G1/S Transition Of Mitotic Cell Cycle
Bergmann Glial Cell Differentiation
Ribonucleoside Diphosphate Catabolic Process
Regulation Of Metabolic Process
Protein Ubiquitination
Circadian Rhythm
Regulation Of Apoptotic DNA Fragmentation
GMP Metabolic Process
Nucleoside Diphosphate Catabolic Process
Protein Modification By Small Protein Conjugation
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Deoxyribonucleoside Diphosphate Metabolic Process
Regulation Of Protein Ubiquitination
Substrate-dependent Cell Migration, Cell Extension
Histone H2A Monoubiquitination
Tagcloud
?
11p12
14q24
6q12
9p24
abcd4
acyp1
amplifications
cd109
cd274
commd9
coq6
cttn
fjx1
hbld1
interscience
jdp2
jpages
ltbp2
myo6
otscc
pdhx
pinpointed
ppfia1
q14
rln1
slc1a1
suppmat
trim44
znf410
Tagcloud (Difference)
?
11p12
14q24
6q12
9p24
abcd4
acyp1
amplifications
cd109
cd274
commd9
coq6
cttn
fjx1
hbld1
interscience
jdp2
jpages
ltbp2
myo6
otscc
pdhx
pinpointed
ppfia1
q14
rln1
slc1a1
suppmat
trim44
znf410
Tagcloud (Intersection)
?