KLHL2 and BCAM

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLHL2	BCAM
Gene Name		kelch-like family member 2	basal cell adhesion molecule (Lutheran blood group)
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding	Transmembrane Signaling Receptor Activity Laminin Receptor Activity Laminin Binding
	Biological Process	Protein Ubiquitination	Cell Adhesion Cell-matrix Adhesion Signal Transduction
Pathways
Drugs
Diseases
GWAS			Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-Protein Interactions		15 interactors: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114	5 interactors: EPB41 KLHL2 LAMA5 SUMO1 UBE2I
Entrez ID		11275	4059
HPRD ID		09311	00197
Ensembl ID		ENSG00000109466	ENSG00000187244
Uniprot IDs		O95198	P50895
PDB IDs		2XN4	2PET 2PF6
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Pancreatic Juice Secretion Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Segregation Negative Regulation Of Transferase Activity Regulation Of Mitotic Nuclear Division COPII Vesicle Coating Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process COPII-coated Vesicle Budding Positive Regulation Of Cellular Protein Catabolic Process Protein Polyubiquitination Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Regulation Of Chromosome Organization Spindle Assembly Checkpoint Protein K48-linked Ubiquitination Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Protein Ubiquitination Mitotic Spindle Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitotic Nuclear Division Protein Monoubiquitination Localization Within Membrane Negative Regulation Of Chromosome Segregation Vesicle Targeting Regulation Of Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Regulation Of Cell Division Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Proteolysis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Catalytic Activity Cellular Protein Modification Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of SUMO Transferase Activity Post-translational Protein Modification PML Body Organization Peptidyl-lysine Modification Regulation Of Binding Protein Localization To Nuclear Pore Protein Localization To Nuclear Envelope Organelle Organization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Protein Localization To Membrane
Tagcloud ?			adam aureus cdt clostridium cnf1 compartments cytosol difficile effectors endosomal enter laminin lipolysis lipoprotein lrp lsr lu machines metalloprotease necrotizing optimized perfringens protocols retrograde staphylococcus toxin toxins tpel transferase
Tagcloud (Difference) ?			adam aureus cdt clostridium cnf1 compartments cytosol difficile effectors endosomal enter laminin lipolysis lipoprotein lrp lsr lu machines metalloprotease necrotizing optimized perfringens protocols retrograde staphylococcus toxin toxins tpel transferase
Tagcloud (Intersection) ?