HIPK2 and SIAH1

  • Number of citations of the paper that reports this interaction (PMID 19250734)
  • 3
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology)

HIPK2

SIAH1

Gene Name homeodomain interacting protein kinase 2 siah E3 ubiquitin protein ligase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 48 interactors: AATF BTRC CHMP4B CREBBP CUL1 CXCL1 DAXX DDX39A DDX39B EP300 FBXW7 HIST2H2BE HMGA1 KAT2B MAP3K7 MBP MDM2 MECP2 MKNK1 MYB MYBL1 NKX2-1 NKX2-5 NKX3-1 NLK PAX6 PML PTCH1 RANBP9 RUNX1 SENP1 SIAH1 SIAH2 SKI SMAD1 SMAD2 SMAD3 SP100 SUMO1 SUMO2 TP53 TP53INP1 TP63 TP73 TRADD UBE2I WSB1 ZBTB4 135 interactors: AASDHPPT AFF1 AFF4 APC AQP1 ARMC9 ATN1 ATXN7 BAG1 BCL6 C14orf105 CACYBP CAPG CDC23 CDC34 CDK5R1 CTNNB1 DAB1 DCC DDX41 DNAJC15 DNALI1 EEF1D EIF3J ELL2 EXOC3-AS1 FAM90A1 FLI1 FZD9 GAPDH GDPD5 GRM5 HIPK2 HIPK3 HIST4H4 INHA KATNAL1 KCNJ10 KHDRBS3 KIAA0319L KIAA1217 KIAA1683 KIF1B KIF22 KIFC3 LACTB2 MAB21L1 MAPK12 MAPKBP1 MAPRE3 MOB3C MTIF3 MX1 MYD88 NELFA NOL6 NUMB NUMBL OPRM1 OTUB2 PEG10 PEG3 PFKM PHC1 PHC2 PIAS1 PIAS2 PIAS3 PKD1 POU2AF1 PRPF31 PRR20A PTPMT1 PUF60 PVRL2 PYGB QRICH1 RAB33A RAD51AP1 RAD54L2 RAPH1 RBBP8 RPL27A RPS19BP1 SDCBP SH3RF1 SLC9A3R2 SNCA SNCAIP SPATA4 SPATC1L STAT3 SYP SYT7 TBC1D22B TERF2 TFDP1 TMEM43 TNK2 TOLLIP TP53BP2 TRIM23 TRIM27 TRIM7 TRIM8 TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 TXN UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2I UBE2K UBE2L6 UBE2N UBE2V2 UPP2 USP19 UXT VAV1 WDYHV1 ZBP1 ZCCHC10 ZCCHC13 ZFYVE21 ZMAT3 ZNF148 ZNF512B ZNF671
Entrez ID 28996 6477
HPRD ID 06039 03736
Ensembl ID ENSG00000064393 ENSG00000196470
Uniprot IDs Q9H2X6 Q8IUQ4
PDB IDs 2A25 4I7B 4I7C 4I7D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adding  complexity  decisions  determines  e3  fail  fate  favoring  feedback  finger  homeodomain  inactivated  interferes  ligase  loop  preferentially  proline  siah2  stimulates  switch  termination  ubiquitin  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  e3  exerts  increases  inducing  inhibiting  introduce  ligase  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  ubiquitin  view  vitamin 
Tagcloud (Difference) ?
adding  complexity  decisions  determines  fail  fate  favoring  feedback  finger  homeodomain  inactivated  interferes  loop  preferentially  proline  siah2  stimulates  switch  termination  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
alleviates  anticancer  appears  cytotoxicity  debatable  decreases  degradation  demonstrating  downregulation  exerts  increases  inducing  inhibiting  introduce  note  oncoprotein  p34sei  partly  polyubiquitination  prerequisite  previous  reveal  stronger  summary  view  vitamin 
Tagcloud (Intersection) ?
e3  ligase  ubiquitin