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RGS17 and OTX1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
RGS17
OTX1
Gene Name
regulator of G-protein signaling 17
orthodenticle homeobox 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Nucleus
Molecular Function
GTPase Activator Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Biological Process
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Anterior/posterior Pattern Specification
Metencephalon Development
Midbrain Development
Inner Ear Morphogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Diencephalon Morphogenesis
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (z) signalling events
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
18 interactors:
ADRB2
AQP1
DHX37
GNAI1
GNAI3
HOXA1
LCE2A
LCE3C
LCE4A
NUFIP2
OSTM1
OTX1
PTGER3
RABEP1
RBBP8
RPL10A
SMCP
TBC1D16
39 interactors:
CHIC2
CHRD
COMP
GEMIN8P4
GRN
KCNK16
KRT81
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2A
LCE2D
LCE4A
MDFI
MGAT5B
RBPMS
RGS17
RGS20
SMARCC1
SPRY1
SPRY2
TLE4
Entrez ID
26575
5013
HPRD ID
06223
08964
Ensembl ID
ENSG00000091844
ENSG00000115507
Uniprot IDs
Q9UGC6
P32242
PDB IDs
1ZV4
Enriched GO Terms of Interacting Partners
?
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Keratinization
Heat Generation
Keratinocyte Differentiation
Membrane Fusion
Epidermal Cell Differentiation
Temperature Homeostasis
Bicarbonate Transport
Vesicle Organization
Skin Development
Regulation Of Body Fluid Levels
Vesicle Fusion
Regulation Of Adenylate Cyclase Activity
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Epidermis Development
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Regulation Of Cyclase Activity
Cellular Response To Retinoic Acid
Organelle Fusion
Facial Nucleus Development
Carbon Dioxide Transmembrane Transport
Corticotropin Secretion
Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Developmental Process
Regulation Of CAMP Biosynthetic Process
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Metanephric Proximal Convoluted Tubule Development
Rhombomere 4 Development
Nitric Oxide Transport
Semicircular Canal Formation
Cellular Response To Mercury Ion
Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure
Renal System Process
Regulation Of CAMP Metabolic Process
Inner Ear Morphogenesis
Membrane Organization
Rhombomere 3 Development
Rhombomere 5 Development
Metanephric Proximal Tubule Development
Fever Generation
Organ Development
Anatomical Structure Development
Keratinization
Keratinocyte Differentiation
Epithelium Development
Epidermis Development
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tissue Development
Epidermal Cell Differentiation
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Bud Elongation Involved In Lung Branching
Skin Development
Organ Development
Developmental Process
Negative Regulation Of Ras GTPase Activity
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Anatomical Structure Development
Branch Elongation Of An Epithelium
Negative Regulation Of Signal Transduction
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Signaling
Negative Regulation Of GTPase Activity
Axis Elongation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Mitotic Spindle Orientation
Multicellular Organismal Development
Establishment Of Mitotic Spindle Localization
Establishment Of Spindle Orientation
Epithelial Tube Branching Involved In Lung Morphogenesis
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
System Development
Spindle Localization
BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning
Epithelial Cell Differentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Ras Protein Signal Transduction
Organ Morphogenesis
Negative Regulation Of Small GTPase Mediated Signal Transduction
Lung Morphogenesis
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Developmental Growth
Regulation Of MAP Kinase Activity
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Organ Growth
Regulation Of GTPase Activity
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Establishment Of Cell Polarity
Tagcloud
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Difference)
?
17q21
2p15
allowing
amplification
antecedent
bcl11a
cdkn2a
cgh
commd1
diffuse
disrupting
dlbcl
dndlbcl
driver
encompassing
exclusively
fl
follicular
lymphoma
never
nfkappabeta
novo
outline
paired
possessed
rel
tdlbcl
transformation
usp34
Tagcloud (Intersection)
?