RGS17 and OSTM1

Number of citations of the paper that reports this interaction (PMID 12826607)
10

Data Source:
HPRD (two hybrid)

		RGS17	OSTM1
Gene Name		regulator of G-protein signaling 17	osteopetrosis associated transmembrane protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activator Activity
	Biological Process	Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Osteoclast Differentiation Ion Transmembrane Transport Transmembrane Transport
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events	Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		18 interactors: ADRB2 AQP1 DHX37 GNAI1 GNAI3 HOXA1 LCE2A LCE3C LCE4A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SMCP TBC1D16	6 interactors: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20
Entrez ID		26575	28962
HPRD ID		06223	09628
Ensembl ID		ENSG00000091844	ENSG00000081087
Uniprot IDs		Q9UGC6	Q86WC4
PDB IDs		1ZV4
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Heat Generation Keratinocyte Differentiation Membrane Fusion Epidermal Cell Differentiation Temperature Homeostasis Bicarbonate Transport Vesicle Organization Skin Development Regulation Of Body Fluid Levels Vesicle Fusion Regulation Of Adenylate Cyclase Activity Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Epidermis Development Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Regulation Of Cyclase Activity Cellular Response To Retinoic Acid Organelle Fusion Facial Nucleus Development Carbon Dioxide Transmembrane Transport Corticotropin Secretion Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Establishment Or Maintenance Of Actin Cytoskeleton Polarity Developmental Process Regulation Of CAMP Biosynthetic Process DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Metanephric Proximal Convoluted Tubule Development Rhombomere 4 Development Nitric Oxide Transport Semicircular Canal Formation Cellular Response To Mercury Ion Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Renal System Process Regulation Of CAMP Metabolic Process Inner Ear Morphogenesis Membrane Organization Rhombomere 3 Development Rhombomere 5 Development Metanephric Proximal Tubule Development Fever Generation Organ Development Anatomical Structure Development	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway DNA Ligation Involved In DNA Recombination Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Regulation Of Catalytic Activity Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Establishment Of Integrated Proviral Latency Negative Regulation Of Signaling Establishment Of Viral Latency Immunoglobulin V(D)J Recombination Regulation Of Signal Transduction DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation Regulation Of Signaling DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Positive Regulation Of Catalytic Activity Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Response To PH Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Response To Gamma Radiation Neuron Apoptotic Process
Tagcloud ?			anhydrase arthritis carbonic cathepsin chalcone clcn7 destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol
Tagcloud (Difference) ?			anhydrase arthritis carbonic cathepsin chalcone clcn7 destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol
Tagcloud (Intersection) ?