RGS17

Description		regulator of G protein signaling 17
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GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Neuron Projection Synapse
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) Fasting glucose ( 34059833) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		45 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HINT1 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN
Entrez ID		26575
HPRD ID		06223
Ensembl ID		ENSG00000091844
Uniprot IDs		Q9UGC6
PDB IDs		1ZV4 6AM3
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development Tissue Development Protein Binding Intermediate Filament Defense Response To Gram-negative Bacterium [2Fe-2S] Cluster Assembly Identical Protein Binding Negative Regulation Of Smooth Muscle Contraction Iron-sulfur Cluster Assembly Complex
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