TFIP11 and DISC1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		TFIP11	DISC1
Gene Name		tuftelin interacting protein 11	disrupted in schizophrenia 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Spliceosomal Complex Cytoplasm Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome	Mitochondrion Centrosome Microtubule Postsynaptic Density Cell Junction Ciliary Basal Body Postsynaptic Membrane
	Molecular Function	DNA Binding	Protein Binding
	Biological Process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated RNA Processing Biomineral Tissue Development	Microtubule Cytoskeleton Organization Neuron Migration Positive Regulation Of Neuroblast Proliferation Regulation Of Neuron Projection Development Cerebral Cortex Radially Oriented Cell Migration Cell Proliferation In Forebrain Positive Regulation Of Wnt Signaling Pathway TOR Signaling Cellular Protein Localization Mitochondrial Calcium Ion Homeostasis Canonical Wnt Signaling Pathway Regulation Of Synapse Maturation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease ( 19118814) Amyotrophic lateral sclerosis ( 19451621) Neuranatomic and neurocognitive phenotypes ( 21483430) Response to antineoplastic agents ( 21659360) Response to statin therapy ( 20339536)
Protein-Protein Interactions		102 interactors: ABI2 ADCK3 AIMP2 ALS2CR11 ANKRD11 ARMCX1 ARNT2 ATP5O BMF C1orf109 C6orf165 CARD9 CCDC116 CCDC121 CCDC146 CCDC151 CCDC42 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CENPU CEP57 CEP57L1 COX5B DGCR6 DISC1 EIF3A FAM13C FAM156A FAM161A FAM50B GCC1 GEM GNG4 GOLGA1 GPS2 HAUS1 HMG20B HOOK1 IKBIP IMP3 KANSL1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5L LENG1 LIN37 LINC00238 LMO1 LMO4 LSP1P3 METTL17 MTFR2 NDC80 NDE1 NDN NFU1 OIP5 PBX4 PDE4DIP POLL PPP1R18 PRPF31 RCOR3 RHNO1 RRP7A S100P SAP30BP SFR1 SH2D4A SH3GLB1 SMARCE1 SNRPB SNW1 SNX20 SSX2IP STRN TCAF1 TFPT THAP7 THAP8 TNNT1 TRAF3IP3 TRAPPC4 TSHZ3 TSPYL4 TUFT1 TXLNA VPS37C ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZSCAN12	113 interactors: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365
Entrez ID		24144	27185
HPRD ID		11628	05553
Ensembl ID		ENSG00000100109	ENSG00000162946
Uniprot IDs		Q9UBB9	C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Mitotic Cell Cycle Cellular Component Assembly Mitotic Cell Cycle Process Cell Cycle Process Cellular Macromolecular Complex Assembly G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Cell Division Mitotic Nuclear Division Nucleosome Organization Chromatin Assembly Or Disassembly Mitotic Cell Cycle Phase Transition Cytoskeleton Organization Cell Cycle Phase Transition Centrosome Organization Microtubule Anchoring Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Organizing Center Organization Chromosome Organization Gene Expression Nucleosome Assembly Microtubule-based Process Maintenance Of Protein Location In Cell Organelle Assembly Maintenance Of Protein Location Chromatin Assembly Maintenance Of Location In Cell Transcription, DNA-templated ATP-dependent Chromatin Remodeling RNA Metabolic Process Anatomical Structure Development Cellular Localization RNA Biosynthetic Process Positive Regulation Of Protein Oligomerization Protein-DNA Complex Assembly Chromatin Organization Ribonucleoprotein Complex Assembly Cellular Macromolecule Biosynthetic Process Recombinational Repair Nucleobase-containing Compound Metabolic Process Protein Targeting To Golgi Chromatin Remodeling Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Macromolecule Biosynthetic Process DNA Packaging CENP-A Containing Nucleosome Assembly Kidney Smooth Muscle Cell Differentiation	Organelle Organization Movement Of Cell Or Subcellular Component Cellular Localization Microtubule-based Process Nervous System Development Establishment Of Localization In Cell Neurogenesis G2/M Transition Of Mitotic Cell Cycle Generation Of Neurons Microtubule Cytoskeleton Organization Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Process Cellular Component Assembly Cell Projection Organization Mitotic Cell Cycle Microtubule-based Transport Cell Cycle Process Organelle Localization Cytoskeleton Organization Cell Cycle Cell Projection Morphogenesis Cell Part Morphogenesis Anatomical Structure Development System Development Membrane Organization Cell Differentiation Cell Morphogenesis Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Organelle Transport Along Microtubule Developmental Process Protein Localization Microtubule-based Movement Axonogenesis Mitotic Nuclear Division Locomotion Establishment Of Organelle Localization Axon Guidance Vesicle Localization Axon Development Neuron Development Cellular Process Regulation Of Cellular Component Organization Multicellular Organismal Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Neurogenesis Cell Projection Assembly Neuron Differentiation Intracellular Transport Spindle Organization
Tagcloud ?			accelerate aggregated allosteric amplify appropriated assemblies assembly biochemically capsid catalytically collections commonality conceptualized continuum crowded exploit governed labile machines multimers multiprotein pathologically prions replicating replicative reprogrammed reset suited transmissibility
Tagcloud (Difference) ?			accelerate aggregated allosteric amplify appropriated assemblies assembly biochemically capsid catalytically collections commonality conceptualized continuum crowded exploit governed labile machines multimers multiprotein pathologically prions replicating replicative reprogrammed reset suited transmissibility
Tagcloud (Intersection) ?