TFIP11 and SFPQ

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TFIP11	SFPQ
Description		tuftelin interacting protein 11	splicing factor proline and glutamine rich
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Nuclear Speck Extracellular Matrix U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck Dendrite Paraspeckles RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Nucleic Acid Binding Protein Binding	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Biomineral Tissue Development Negative Regulation Of Protein-containing Complex Assembly Protection From Non-homologous End Joining At Telomere Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Immune System Process DNA Repair DNA Recombination Chromatin Remodeling Regulation Of DNA-templated Transcription MRNA Processing DNA Damage Response RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Chromosome Organization Regulation Of Cell Cycle Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		mRNA Splicing - Major Pathway	PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
Drugs			Copper Artenimol
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)
Interacting Genes		270 interacting genes: AARD ABI2 ABLIM3 AIMP2 AIRIM ANKRD11 AP1M1 ARHGEF9 ARMC7 ARMCX1 ARNT2 ATP5PO ATPAF2 AXIN1 BAG4 BAZ2B BCAS2 BCL6 BHLHA9 BICD2 BMF BRD1 BYSL CARD9 CATSPERT CAVIN3 CBX8 CCDC102B CCDC116 CCDC120 CCDC121 CCDC13 CCDC146 CCDC187 CCDC196 CCDC42 CCDC57 CCDC6 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CDKN1A CDR2L CENPU CEP55 CEP57 CEP57L1 CEP95 CFAP206 COQ8A COX5B CPEB2 CPSF7 CT55 CWF19L2 DAXX DDX25 DES DGCR6 DHX16 DISC1 DPPA3 DSCAM DTNB EAF2 EIF3A EIF3D ENKD1 ENOX2 EPM2AIP1 EXOC3L1 EXOC8 EXOSC5 EXOSC7 EXOSC8 FAM13C FAM156A FAM161A FAM161B FAM50B FAM81A FAM90A1 FANCG FGA GADD45GIP1 GAS2L2 GCC1 GCFC2 GEM GFAP GNG4 GNL3L GOLGA1 GOLGA2 GPS2 GRAP2 GSE1 HAUS1 HDAC4 HIP1R HMG20B HOOK1 HSF2BP IKBIP IL16 IMP3 JRK KANK2 KANSL1 KAT5 KDM1A KIF20A KIF3C KIF9 KIFC3 KIZ KRT1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5 LCA5L LENG1 LIN37 LMNA LMNB2 LMO1 LMO2 LMO4 LNX1 LSP1P3 LYSMD1 MAB21L2 MAGOH MCM7 MDM2 MED1 METTL17 MFAP1 MKRN3 MRPL11 MTCL2 MTFR2 MYO15B MYO1D MYOM1 NDC80 NDE1 NDN NEK6 NFKBID NFU1 NSMF NUP88 NXF1 ODAD3 OIP5 PBX3 PBX4 PCM1 PDE4DIP PHF1 PIBF1 PICK1 PKN3 PLK4 POLL POLR1C POM121 PPFIA3 PPP1R16A PPP1R16B PPP1R18 PRC1 PRPF18 PRPF31 PRPF6 PSMA4 PSMC5 PSTPIP1 PTCD1 RBBP6 RBM22 RBM7 RCOR3 RHNO1 RIN1 RNF10 RNF6 RPL23A RPUSD3 RRP7A RUNX1T1 RXRB S100P SAP30BP SCNM1 SF1 SFPQ SFR1 SGF29 SH2D4A SH3GLB1 SHANK3 SMARCB1 SMARCE1 SNAPIN SNRNP48 SNRPA SNRPB SNRPN SNW1 SNX20 SNX32 SPG21 SSX2IP STRA8 STRN SUGP1 SYCE1 TBC1D30 TBRG4 TCAF1 TDP2 TFPT THAP7 THAP8 THOC1 TNNT1 TP53 TRAF3IP3 TRAPPC4 TRIM45 TRIML2 TSC1 TSG101 TSGA10IP TSHZ2 TSHZ3 TSPYL4 TUFT1 TXLNA TXN2 UBTFL1 UNKL USP2 USP6 USP7 UTP14A UTP6 VPS37C VPS39 WAC WASHC3 WBP4 ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZNF572 ZNF587 ZNF777 ZSCAN12	120 interacting genes: APBB1 AR CD2BP2 CEBPA CEP55 CPSF7 CSNK2A1 CTTN DDX17 DMRTB1 ERG ESR1 EXOSC5 EXOSC8 FHL2 FMR1 FUS FXR1 FXR2 GAS7 H3-4 JPT1 KRT31 LAMTOR5 LINC00624 LINC01554 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NONO OGT PIN1 PPARG PRPF40A PSPC1 PTBP1 RAC1 SF1 SF3B4 SIN3A SMAD5 SNRPA SREK1 TCERG1 TFIP11 TOP1 UBC UBE2I VIM WBP4 ZMYM2
Entrez ID		24144	6421
HPRD ID		11628	07284
Ensembl ID		ENSG00000100109	ENSG00000116560
Uniprot IDs		Q9UBB9	A0A384N5Z8 P23246 Q86VG2
PDB IDs		8RO2	4WII 4WIJ 4WIK 5WPA 6NCQ 6OWJ 6WMZ 7LRQ 7LRU 7PU5 7SP0 7UJ1 7UK1
Enriched GO Terms of Interacting Partners?		Protein Binding Centrosome Cytoskeleton Spliceosomal Complex Microtubule-based Process Nucleoplasm Nucleus MRNA Metabolic Process MRNA Processing Microtubule Cytoskeleton Organization MRNA Splicing, Via Spliceosome Cytoskeleton Organization Nuclear Speck RNA Splicing, Via Transesterification Reactions RNA Splicing Organelle Organization RNA Processing RNA Metabolic Process Cytoplasm Microtubule Organizing Center Organization Nucleic Acid Metabolic Process Centriole Nucleolus U4/U6 X U5 Tri-snRNP Complex SnRNP Binding Cilium Organization Cellular Component Assembly Identical Protein Binding Microtubule Regulation Of Vitamin D Receptor Signaling Pathway U2-type Precatalytic Spliceosome Microtubule Binding General Transcription Initiation Factor Binding Microtubule Anchoring Microtubule Anchoring At Microtubule Organizing Center Nuclear Matrix Macromolecule Metabolic Process Chromatin Organization Kinesin Complex Exoribonuclease Complex Centrosome Cycle Intermediate Filament Cytoskeleton Epigenetic Regulation Of Gene Expression P53 Binding DNA-binding Transcription Factor Binding Intermediate Filament Organization Microtubule-based Movement Structural Constituent Of Cytoskeleton U4 SnRNA 3'-end Processing Intermediate Filament	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Motility Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Locomotion Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Cytokine Production Negative Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Endothelial Cell Migration Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Developmental Process
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