TFIP11 and EIF3A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TFIP11	EIF3A
Gene Name		tuftelin interacting protein 11	eukaryotic translation initiation factor 3, subunit A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Spliceosomal Complex Cytoplasm Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	DNA Binding	Translation Initiation Factor Activity Structural Molecule Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated RNA Processing Biomineral Tissue Development	Formation Of Translation Preinitiation Complex Formation Of Cytoplasmic Translation Initiation Complex Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways			Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		102 interactors: ABI2 ADCK3 AIMP2 ALS2CR11 ANKRD11 ARMCX1 ARNT2 ATP5O BMF C1orf109 C6orf165 CARD9 CCDC116 CCDC121 CCDC146 CCDC151 CCDC42 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CENPU CEP57 CEP57L1 COX5B DGCR6 DISC1 EIF3A FAM13C FAM156A FAM161A FAM50B GCC1 GEM GNG4 GOLGA1 GPS2 HAUS1 HMG20B HOOK1 IKBIP IMP3 KANSL1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5L LENG1 LIN37 LINC00238 LMO1 LMO4 LSP1P3 METTL17 MTFR2 NDC80 NDE1 NDN NFU1 OIP5 PBX4 PDE4DIP POLL PPP1R18 PRPF31 RCOR3 RHNO1 RRP7A S100P SAP30BP SFR1 SH2D4A SH3GLB1 SMARCE1 SNRPB SNW1 SNX20 SSX2IP STRN TCAF1 TFPT THAP7 THAP8 TNNT1 TRAF3IP3 TRAPPC4 TSHZ3 TSPYL4 TUFT1 TXLNA VPS37C ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZSCAN12	16 interactors: BBS1 BBS4 CACNA1A EIF3B EIF3G EIF3I EIF3J EIF4B EIF4G1 EIF4G2 FBXO32 REL RNF139 TFIP11 UPF1 YWHAZ
Entrez ID		24144	8661
HPRD ID		11628	03618
Ensembl ID		ENSG00000100109	ENSG00000107581
Uniprot IDs		Q9UBB9	F5H335 Q14152
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Mitotic Cell Cycle Cellular Component Assembly Mitotic Cell Cycle Process Cell Cycle Process Cellular Macromolecular Complex Assembly G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Cell Division Mitotic Nuclear Division Nucleosome Organization Chromatin Assembly Or Disassembly Mitotic Cell Cycle Phase Transition Cytoskeleton Organization Cell Cycle Phase Transition Centrosome Organization Microtubule Anchoring Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Organizing Center Organization Chromosome Organization Gene Expression Nucleosome Assembly Microtubule-based Process Maintenance Of Protein Location In Cell Organelle Assembly Maintenance Of Protein Location Chromatin Assembly Maintenance Of Location In Cell Transcription, DNA-templated ATP-dependent Chromatin Remodeling RNA Metabolic Process Anatomical Structure Development Cellular Localization RNA Biosynthetic Process Positive Regulation Of Protein Oligomerization Protein-DNA Complex Assembly Chromatin Organization Ribonucleoprotein Complex Assembly Cellular Macromolecule Biosynthetic Process Recombinational Repair Nucleobase-containing Compound Metabolic Process Protein Targeting To Golgi Chromatin Remodeling Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Macromolecule Biosynthetic Process DNA Packaging CENP-A Containing Nucleosome Assembly Kidney Smooth Muscle Cell Differentiation	Regulation Of Translational Initiation Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Translational Initiation Formation Of Translation Preinitiation Complex Translation Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Gene Expression Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Cellular Component Assembly Ribonucleoprotein Complex Biogenesis Regulation Of Metabolic Process Nonmotile Primary Cilium Assembly Nuclear-transcribed MRNA Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Catabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Photoreceptor Cell Maintenance RNA Catabolic Process Cellular Metabolic Process MRNA Metabolic Process Cellular Response To Hormone Stimulus Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Macromolecular Complex Assembly Cellular Protein Metabolic Process Cerebellar Molecular Layer Development Spliceosomal Complex Disassembly Retina Homeostasis Response To Cytokine MRNA 3'-end Processing Vestibular Nucleus Development Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Metabolic Process Positive Regulation Of Cilium Assembly Cerebellum Maturation Sensory Processing Musculoskeletal Movement, Spinal Reflex Action Regulation Of Cellular Process RNA 3'-end Processing MRNA Processing Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Golgi Reassembly Gamma-aminobutyric Acid Secretion Response To Hormone Cytokine-mediated Signaling Pathway Aromatic Compound Catabolic Process
Tagcloud ?			43s coerce compartmentalization compartmentalize compartmentalized concentrating evolve exited factories factory machinery margins nonstructural obstacle orthoreoviruses pic preinitiation ps6r reentered reovirus reoviruses ribopuromycylation sigmans spatiotemporally synthesizing tubulovesicular undertook vf visualize
Tagcloud (Difference) ?			43s coerce compartmentalization compartmentalize compartmentalized concentrating evolve exited factories factory machinery margins nonstructural obstacle orthoreoviruses pic preinitiation ps6r reentered reovirus reoviruses ribopuromycylation sigmans spatiotemporally synthesizing tubulovesicular undertook vf visualize
Tagcloud (Intersection) ?