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RUSC1 and WWP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
RUSC1
WWP2
Gene Name
RUN and SH3 domain containing 1
WW domain containing E3 ubiquitin protein ligase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome
Golgi Apparatus
Microtubule
Postsynaptic Density
Microtubule Cytoskeleton
Cytoplasmic Membrane-bounded Vesicle
Cell Junction
Cytoplasmic Vesicle
Postsynaptic Membrane
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Membrane
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
SH3/SH2 Adaptor Activity
Protein Binding
RNA Polymerase II Transcription Factor Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transcription Factor Binding
Ligase Activity
Biological Process
Protein Polyubiquitination
Positive Regulation Of Signal Transduction
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Protein Modification Process
Negative Regulation Of Gene Expression
Protein Ubiquitination
Negative Regulation Of Transporter Activity
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Negative Regulation Of Protein Transport
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS
IgE levels (
23146381
)
Protein-Protein Interactions
7 interactors:
APP
FAM9B
NTRK1
PNMA1
RBPMS
STUB1
WWP2
53 interactors:
ANKRD44
ARRDC1
ATN1
CDC34
CLCN5
CPSF6
DAG1
DIDO1
EGR2
EWSR1
FAM189A2
FBXL18
HNRNPUL1
IL2RG
IL6R
LGALS9B
NDFIP2
PAIP1
PDLIM7
POLR2A
POU5F1
RASA1
RNF11
RUSC1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SF1
SFTPC
SMAD3
SMAD7
SNRPC
SPG20
TFAP2A
TNK2
TP53BP2
TRAF4
UBC
UBE2D2
UBE2D3
UBE2E1
UBE2E3
UBE2J2
UBE2K
UBE2L3
USP7
VASP
VPS37C
WBP1
WBP2
WIPF1
Entrez ID
23623
11060
HPRD ID
10206
03812
Ensembl ID
ENSG00000160753
ENSG00000198373
Uniprot IDs
B3KWM9
B4DQB8
Q5T9V0
Q9BVN2
B4DHF6
O00308
PDB IDs
4GIW
Enriched GO Terms of Interacting Partners
?
Protein K63-linked Ubiquitination
Protein Autoubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Synaptic Growth At Neuromuscular Junction
Regulation Of Protein Binding
Regulation Of Cellular Protein Metabolic Process
Collateral Sprouting In Absence Of Injury
Protein Polyubiquitination
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Axonogenesis Involved In Innervation
Axon Choice Point Recognition
Ubiquitin-dependent SMAD Protein Catabolic Process
Regulation Of Protein Phosphorylation
Proteasomal Protein Catabolic Process
Regulation Of Binding
Positive Regulation Of Cellular Metabolic Process
Learning Or Memory
Olfactory Nerve Development
Cellular Response To Nicotine
Cognition
Positive Regulation Of Proteolysis
Neuron Remodeling
Regulation Of Signal Transduction
Response To Hydrostatic Pressure
Locomotion
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Phosphorylation
Regulation Of Glucocorticoid Metabolic Process
Nerve Growth Factor Signaling Pathway
Regulation Of Signaling
Positive Regulation Of SMAD Protein Import Into Nucleus
Misfolded Or Incompletely Synthesized Protein Catabolic Process
Cellular Response To Misfolded Protein
Axon Guidance
Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Response To Misfolded Protein
Cellular Protein Modification Process
Regulation Of Phosphorus Metabolic Process
Regulation Of SMAD Protein Import Into Nucleus
Positive Regulation Of Catalytic Activity
Cellular Copper Ion Homeostasis
Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain
Positive Regulation Of Metabolic Process
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Response To Stimulus
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Excretion
Response To Organic Substance
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cellular Protein Metabolic Process
Protein K11-linked Ubiquitination
Sodium Ion Homeostasis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Gene Expression
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Stimulus
Positive Regulation Of Ossification
Regulation Of Ossification
RNA Biosynthetic Process
Regulation Of Protein Ubiquitination
Apoptotic Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization
Regulation Of Cellular Protein Metabolic Process
Viral Process
Apoptotic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Protein Catabolic Process
RNA Processing
Multicellular Organismal Water Homeostasis
Programmed Cell Death
Negative Regulation Of Transcription By Competitive Promoter Binding
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Proteolysis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Difference)
?
accelerating
anticancer
biomarker
cascade
catalyzes
contributes
counterparts
deleted
dramatic
e3
encodes
final
homologue
ligase
ligases
malignancies
member
nedd4
neoplastic
oscc
osccs
pi3k
promotion
pten
ten
tensin
tumoral
ubiquitination
Tagcloud (Intersection)
?