RUSC1

Gene Name		RUN and SH3 domain containing 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Golgi Apparatus Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Cell Junction Cytoplasmic Vesicle Postsynaptic Membrane
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Protein Polyubiquitination Positive Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: APP FAM9B NTRK1 PNMA1 RBPMS STUB1 WWP2
Entrez ID		23623
HPRD ID		10206
Ensembl ID		ENSG00000160753
Uniprot IDs		B3KWM9 B4DQB8 Q5T9V0 Q9BVN2
PDB IDs		4GIW
Enriched GO Terms of Interacting Partners?		Protein K63-linked Ubiquitination Protein Autoubiquitination Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Synaptic Growth At Neuromuscular Junction Regulation Of Protein Binding Regulation Of Cellular Protein Metabolic Process Collateral Sprouting In Absence Of Injury Protein Polyubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Axonogenesis Involved In Innervation Axon Choice Point Recognition Ubiquitin-dependent SMAD Protein Catabolic Process Regulation Of Protein Phosphorylation Proteasomal Protein Catabolic Process Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Learning Or Memory Olfactory Nerve Development Cellular Response To Nicotine Cognition Positive Regulation Of Proteolysis Neuron Remodeling Regulation Of Signal Transduction Response To Hydrostatic Pressure Locomotion Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Phosphorylation Regulation Of Glucocorticoid Metabolic Process Nerve Growth Factor Signaling Pathway Regulation Of Signaling Positive Regulation Of SMAD Protein Import Into Nucleus Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Axon Guidance Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Response To Misfolded Protein Cellular Protein Modification Process Regulation Of Phosphorus Metabolic Process Regulation Of SMAD Protein Import Into Nucleus Positive Regulation Of Catalytic Activity Cellular Copper Ion Homeostasis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Positive Regulation Of Metabolic Process
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