RUSC1 and PM20D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RUSC1	PM20D2
Description		RUN and SH3 domain containing 1	peptidase M20 domain containing 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytosol Cytoskeleton Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Vesicle Synapse	Nucleoplasm Cytoplasm
	Molecular Function	Actin Binding Protein Binding	Carboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity
	Biological Process	Protein Polyubiquitination	Proteolysis Folic Acid Catabolic Process Regulation Of Protein Metabolic Process
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Serum metabolite levels ( 33031748)
Interacting Genes		92 interacting genes: ABHD11 ABHD5 ABI2 AIRIM AKAP8L ANKS1A APP ATP6V0D2 BPIFA1 CCDC120 CCDC57 CCHCR1 CCNC CDKN2B CMTM6 CREM CRYBA2 CTAG1A CTAG1B DMRT3 DOK6 DTX2 DVL2 EXOC8 EXOSC8 FAM9B FNDC3B GCM2 HMG20A HNRNPF INSC KCTD9 KRTAP19-1 KRTAP19-5 KRTAP6-2 KRTAP8-1 LIMS3 LIMS4 LMO2 MAGEA3 MAGEA6 MAGED1 MED25 MEIS2 MISP MOAP1 MORN3 MYOZ3 N4BP3 NICN1 NTAQ1 NTRK1 NUDT22 OIP5 P4HA3 PFDN5 PIK3R3 PLA2G6 PM20D2 PNMA1 POLR1C PRDM14 PRR35 RBPMS SMARCB1 SMYD1 SOHLH1 SPAG8 STUB1 SUOX TBC1D25 TCHP TEKT4 TENT5B TLE5 TRAPPC6A TRIM55 TRIM63 TRIM73 TSSK3 TTC19 TTC7B UFSP1 VGLL3 WWOX WWP2 ZIC1 ZMYND12 ZNF34 ZNF620 ZNF765 ZNF77	24 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 OGT POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2
Entrez ID		23623	135293
HPRD ID		10206	16473
Ensembl ID		ENSG00000160753	ENSG00000146281
Uniprot IDs		A0A8Q3SIT1 B4DQB8 Q9BVN2	Q8IYS1
PDB IDs		4GIW	7YH4 8XZC
Enriched GO Terms of Interacting Partners?		Protein Binding
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